Detailed information NTG0757906

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ORT68_RS00180
• Genome accession: NZ_CP111111
• Coordinates: 39341..40690 (-)
• Length: 449 a.a.
• NCBI ID: WP_259980403.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain KCTC 13172
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	37691..40690	39341..40690	within	0

Gene organization within MGE regions

Location: 37691..40690

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ORT68_RS00175 (ORT68_00175)	ccrB	37691..39319 (-)	1629	WP_002511343.1	cassette chromosome recombinase CcrB	Machinery gene
ORT68_RS00180 (ORT68_00180)	ccrA	39341..40690 (-)	1350	WP_259980403.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52667.53 Da
• Isoelectric Point: 9.9831

>NTDB_id=757906 ORT68_RS00180 WP_259980403.1 39341..40690(-) (ccrA) [Staphylococcus epidermidis strain KCTC 13172]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDDTFINRQPYQVRNIIMNPNYCGRVINQYGQFDNMFPSIVSAKI
YELAQKLRSQKQTKQTPSDNQLKQKIKCPYCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDHHIYAKIKNAIDKRLKRQRNTETHHTLTQEKLIEKLAQGIIDAETFRKQMQSLHQQPQRITSISEHQIQHTIQ
NIIQKRFTLNILYPYIETIHIAKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=757906 ORT68_RS00180 WP_259980403.1 39341..40690(-) (ccrA) [Staphylococcus epidermidis strain KCTC 13172]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGACTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAAAAAATTGCACAGTTATTAGAAGAAGATGATACGTTCATCAATCGACAACCTTATCAAGTTCGTAATATTATCATGA
ACCCTAATTATTGTGGTCGTGTTATCAACCAATACGGTCAATTCGACAATATGTTCCCTTCTATTGTTTCGGCAAAAATA
TATGAACTAGCGCAGAAACTTCGATCGCAAAAACAAACCAAACAGACACCTTCAGATAATCAACTAAAACAAAAAATCAA
ATGCCCATATTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAAACATTGGAAGATAAAGTATTAAAAGTG
TGCCAAGACTTTTATCAAGACCACCATATCTACGCAAAAATTAAAAATGCGATTGACAAACGCTTAAAAAGACAACGAAA
CACAGAAACACATCACACACTGACTCAAGAAAAACTAATAGAAAAGTTAGCCCAAGGCATCATCGATGCAGAAACGTTCA
GAAAACAAATGCAATCATTACATCAACAACCGCAACGCATCACATCCATCAGTGAGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTGAACATATTGTACCCCTATATTGAAACCATTCACATTGCGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (4-147)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-322)

• Recombinase (Recombinase) (169-250)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	92.428	100	0.924
ccrA	Staphylococcus aureus COL	75.056	100	0.751