Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   HPK28_RS10220 Genome accession   NZ_CP110417
Coordinates   2255243..2257057 (-) Length   604 a.a.
NCBI ID   WP_050338374.1    Uniprot ID   F6IXG6
Organism   Lactiplantibacillus pentosus strain OHF 23     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2250243..2262057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPK28_RS10200 (HPK28_10200) - 2251857..2252759 (-) 903 WP_050338377.1 RluA family pseudouridine synthase -
  HPK28_RS10205 (HPK28_10205) - 2252756..2253559 (-) 804 WP_003639098.1 NAD kinase -
  HPK28_RS10210 (HPK28_10210) - 2253556..2254218 (-) 663 WP_050338376.1 GTP pyrophosphokinase -
  HPK28_RS10215 (HPK28_10215) - 2254512..2255147 (+) 636 WP_050338375.1 DsbA family protein -
  HPK28_RS10220 (HPK28_10220) pepF 2255243..2257057 (-) 1815 WP_050338374.1 oligoendopeptidase F Regulator
  HPK28_RS10225 (HPK28_10225) - 2257129..2258220 (-) 1092 WP_050338373.1 competence protein CoiA -
  HPK28_RS10230 (HPK28_10230) - 2258554..2259285 (-) 732 WP_003639103.1 adaptor protein MecA -
  HPK28_RS10235 (HPK28_10235) spxA 2259421..2259819 (-) 399 WP_050338372.1 transcriptional regulator SpxA -
  HPK28_RS10240 (HPK28_10240) - 2260333..2261076 (-) 744 WP_050338371.1 MBL fold metallo-hydrolase -
  HPK28_RS10245 (HPK28_10245) - 2261218..2261718 (+) 501 WP_050338370.1 hypothetical protein -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 67891.07 Da        Isoelectric Point: 5.0704

>NTDB_id=754936 HPK28_RS10220 WP_050338374.1 2255243..2257057(-) (pepF) [Lactiplantibacillus pentosus strain OHF 23]
MVATKQLPTRSAVPEELTWDLTPIYATQAAYEADVAQVKAALTAVTALKEHFTDSADTVLAGIQAVLDVYRRLEKVAVYA
SLKSDQDTGNSTNAALDDQASSLTAKVSAATAWFEPAILQLTPDELDTYLDQNVTLRDYRHLLDTVRLQKGHVLSENEES
LLAGASDIFGASAKTFGVLNNADFKFPTVKDDDGNPVTLSQGLYGVLLESVHPAVRREAFEALYRVYSQFRRTLASTLAS
QVKVHNFVAQAHHYPDARAAALAANQIPTSVYDALVTSVDDHLDLLHRYVALRKRLLGVDQLHMYDMYTPLAEKPAIKYT
YQQAQTTALQALKILGPDYIKHVKTAFGSRWIDVVENQGKRSGAYSSGMYDTAPYMLLNWQDNIDNLYTLVHEMGHSMHS
YFTTHNQPYQYGDYSIFVAEIASTTNENLLTNYFLETEKDPKMRAYVLNYYLDGFKGTVFRQTQFAEFEQWIHEQDQAGQ
ALTADRLSKYYLQLNQRYYGDAVVSDPQIADEWSRIPHFYYNYYVYQYATGFAAASTLAERISSKQPDAVTDYLGYLKAG
SSAFPIDVMHRAGVDMTKPDYLDAAFKVFAERLDEFEQLVTAAQ

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=754936 HPK28_RS10220 WP_050338374.1 2255243..2257057(-) (pepF) [Lactiplantibacillus pentosus strain OHF 23]
ATGGTAGCAACCAAACAATTGCCGACCCGTTCAGCCGTTCCTGAAGAACTGACTTGGGATCTGACCCCAATCTACGCCAC
TCAGGCTGCGTATGAAGCGGATGTCGCGCAGGTTAAAGCCGCACTGACAGCTGTGACGGCATTGAAAGAACATTTTACGG
ACTCCGCTGATACCGTATTAGCAGGGATTCAGGCTGTCCTGGATGTTTATCGACGGCTTGAAAAGGTCGCCGTGTACGCG
AGCTTGAAGAGTGACCAGGACACTGGCAACAGCACCAACGCCGCACTCGACGATCAGGCTAGCAGCTTAACGGCCAAGGT
ATCCGCCGCCACTGCCTGGTTTGAACCGGCAATTTTGCAATTAACACCGGATGAACTTGATACTTATTTGGATCAAAACG
TCACATTACGTGATTATCGGCACTTACTCGATACTGTCCGGCTCCAGAAGGGGCACGTTTTATCAGAAAACGAAGAGTCA
TTACTTGCTGGTGCCAGTGATATTTTTGGCGCGTCAGCGAAGACCTTTGGCGTCTTGAACAATGCTGACTTCAAGTTTCC
AACAGTCAAGGATGATGACGGTAACCCAGTGACCCTTTCGCAGGGGTTATATGGCGTGTTGCTAGAATCAGTGCATCCAG
CCGTTCGTCGCGAAGCGTTTGAAGCGTTATACCGGGTTTATAGCCAGTTTCGGCGGACCCTTGCTTCAACCCTAGCGAGT
CAAGTAAAGGTGCATAACTTTGTCGCTCAGGCGCATCACTATCCGGATGCGCGGGCAGCGGCGTTAGCAGCCAACCAGAT
TCCAACGTCAGTTTATGACGCGCTAGTGACATCGGTTGATGACCATCTGGACTTATTACATCGTTACGTGGCCCTCCGTA
AACGGCTGCTGGGGGTAGACCAATTGCATATGTATGATATGTATACACCATTGGCTGAGAAGCCTGCCATCAAATATACT
TATCAGCAAGCCCAGACCACGGCATTACAGGCGTTAAAGATTTTAGGCCCAGATTACATCAAACACGTCAAGACGGCCTT
TGGTTCACGGTGGATCGATGTGGTTGAAAATCAAGGTAAGCGGAGTGGGGCATATTCATCAGGCATGTATGATACGGCGC
CATATATGCTCTTAAATTGGCAAGACAATATCGATAACTTGTACACGCTCGTCCACGAGATGGGACATAGTATGCACTCA
TACTTCACGACCCATAATCAGCCTTATCAGTATGGTGACTATTCGATCTTTGTGGCTGAAATTGCATCGACGACCAACGA
AAACTTGCTGACTAATTATTTCTTGGAGACTGAAAAGGACCCTAAGATGCGGGCGTATGTTTTGAATTACTATCTCGACG
GCTTCAAGGGGACGGTCTTCCGTCAAACGCAATTTGCTGAATTCGAACAATGGATTCATGAACAAGACCAAGCAGGGCAA
GCTTTGACCGCTGACCGGCTATCGAAATACTACTTGCAACTCAATCAACGCTACTACGGTGACGCGGTGGTCAGTGATCC
GCAGATTGCGGATGAATGGTCCCGAATTCCGCATTTCTACTACAACTATTACGTCTACCAGTATGCGACTGGTTTCGCGG
CGGCTTCGACATTGGCTGAACGGATCAGTAGTAAGCAACCAGACGCAGTTACGGATTATCTGGGGTATCTGAAGGCGGGG
TCTTCGGCGTTCCCAATCGATGTGATGCATCGTGCGGGTGTCGATATGACTAAGCCGGATTACTTGGATGCTGCATTCAA
AGTGTTTGCTGAACGCTTGGATGAATTTGAACAATTGGTGACTGCTGCCCAATAG

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(118-186)

Peptidase family M3 (Peptidase_M3)

(207-587)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F6IXG6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

52.872

98.013

0.518