Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   UKS_RS01535 Genome accession   NZ_AP021887
Coordinates   292977..293801 (+) Length   274 a.a.
NCBI ID   WP_156011485.1    Uniprot ID   -
Organism   Streptococcus sp. 116-D4     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 287977..298801
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UKS_RS01500 (UKS_02690) asnA 288067..289059 (+) 993 WP_049496233.1 aspartate--ammonia ligase -
  UKS_RS01505 (UKS_02700) rsmD 289124..289663 (+) 540 WP_049496231.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  UKS_RS01510 (UKS_02710) coaD 289653..290141 (+) 489 WP_049496228.1 pantetheine-phosphate adenylyltransferase -
  UKS_RS01515 (UKS_02720) sepM 290125..291162 (+) 1038 WP_156011479.1 SepM family pheromone-processing serine protease Regulator
  UKS_RS01520 (UKS_02730) - 291220..291450 (+) 231 WP_080977062.1 DUF1146 family protein -
  UKS_RS01525 (UKS_02740) murA 291474..292757 (+) 1284 WP_156011481.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  UKS_RS01530 (UKS_02750) - 292750..292938 (+) 189 WP_173020490.1 DNA-directed RNA polymerase subunit beta -
  UKS_RS01535 (UKS_02760) endA 292977..293801 (+) 825 WP_156011485.1 DNA-entry nuclease EndA Machinery gene
  UKS_RS01540 (UKS_02770) - 294044..295375 (+) 1332 WP_049496219.1 hemolysin family protein -
  UKS_RS01550 (UKS_02780) amiA3 295801..297789 (+) 1989 WP_156011487.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29884.63 Da        Isoelectric Point: 9.8711

>NTDB_id=75333 UKS_RS01535 WP_156011485.1 292977..293801(+) (endA) [Streptococcus sp. 116-D4]
MDKKTRQALIGLLVLLLLSAGSYYIQQMQLIPNSPKTKVSQKKQAAEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKSTRQYKNREETGNGSTSWTPPGWHQVKNLKGAYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESMVRKALDQNKRVRYRVTLYYASKEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=75333 UKS_RS01535 WP_156011485.1 292977..293801(+) (endA) [Streptococcus sp. 116-D4]
ATGGATAAAAAAACAAGACAGGCACTGATCGGACTGCTAGTGTTATTACTCTTATCTGCAGGGAGCTACTATATCCAGCA
GATGCAGTTGATACCAAATAGTCCCAAAACCAAAGTTAGTCAGAAAAAACAAGCTGCTGAAGCTCCTAGTCAAGCATTGG
CAGAAAGTGTCTTAACAGACGCAGTCAAAAGCCAAATAAAAGGGAGTCTTGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCTTACGCTGATAATAAAACAAAGACAGTTGGCAAGGA
AACCGTGCCAACTGTAGCAAATGCCCTCTTGTCTAAGTCTACTCGCCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CGACTTCTTGGACTCCTCCAGGCTGGCATCAGGTTAAGAATCTAAAGGGGGCTTATACCCATGCGGTTGATAGAGGTCAC
TTGTTAGGATATGCCTTAATCGGTGGCTTGGATGGTTTTGATGCCTCGACAAGCAATCCTAAAAATATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAGGCAGAGGATTCGACTGGTCAAAACTACTATGAAAGCATGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGCTACCGTGTAACCCTCTATTACGCTTCAAAAGAGGACCTAGTTCCTTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGACGGGGAATTGGAATTTAACGTCCTAGTTCCCAATGTTCAAAAGGGGCTTCAACTGGATTACCGAAC
TGGAGAAGTGACTGTTACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

94.161

100

0.942
  endA Streptococcus pneumoniae D39

94.161

100

0.942
  endA Streptococcus pneumoniae R6

94.161

100

0.942
  endA Streptococcus pneumoniae TIGR4

94.161

100

0.942

Multiple sequence alignment