Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   A6U93_RS01960 Genome accession   NZ_CP123838
Coordinates   388360..390180 (-) Length   606 a.a.
NCBI ID   WP_065658275.1    Uniprot ID   A0AA44F0C8
Organism   Agrobacterium tumefaciens strain 15-1187-1-2a     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 383360..395180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6U93_RS01935 (A6U93_01935) - 384040..384279 (+) 240 WP_019564234.1 DUF4170 domain-containing protein -
  A6U93_RS01940 (A6U93_01940) waaA 384495..385817 (+) 1323 WP_013635565.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  A6U93_RS01945 (A6U93_01945) - 385811..386548 (+) 738 WP_019564232.1 HAD family hydrolase -
  A6U93_RS01950 (A6U93_01950) lpxK 386713..387759 (+) 1047 WP_065658276.1 tetraacyldisaccharide 4'-kinase -
  A6U93_RS01955 (A6U93_01955) - 387989..388210 (-) 222 WP_003519053.1 DUF2093 domain-containing protein -
  A6U93_RS01960 (A6U93_01960) hexB 388360..390180 (-) 1821 WP_065658275.1 DNA mismatch repair endonuclease MutL Machinery gene
  A6U93_RS01965 (A6U93_01965) - 390588..392207 (+) 1620 WP_065658306.1 response regulator -
  A6U93_RS01970 (A6U93_01970) - 392350..393702 (+) 1353 WP_003519050.1 putative bifunctional diguanylate cyclase/phosphodiesterase -
  A6U93_RS01975 (A6U93_01975) - 393797..394684 (-) 888 WP_065658274.1 SMP-30/gluconolactonase/LRE family protein -

Sequence

Protein


Download         Length: 606 a.a.        Molecular weight: 65097.80 Da        Isoelectric Point: 6.4000

>NTDB_id=752718 A6U93_RS01960 WP_065658275.1 388360..390180(-) (hexB) [Agrobacterium tumefaciens strain 15-1187-1-2a]
MAIKQLSETLINQIAAGEVIERPSSATKELVENAIDAGATRIEIATAGGGKGLVRITDNGSGMSPADLELAVRRHCTSKI
STTLDDIRTLGFRGEALPSIGSVAKLSITSRQHGAEQGSVISVTGGKVSEVRPAAANAGTIVEVRDLFFATPARLKFLKT
ERAEAAAITEVVKRMAIAFPHIRFVLSGTDRSTLEIPSTGDDHLARMAQILGAEFKDNAIEIDAGREDVTLSGFAGVPTF
NRGNSAHQYVFVNGRPVQDKLLLSAIRGAYAETVPHGRYPVAVLSLTLDPAFVDVNVHPAKSDVRFRDPGLVRGLIVGAI
RQALTRDGDRAATTGASQMMNAFRPGYSPSNLRPSAAATWSAAASPSRPLAVSGNMQFAEAVQSRFSDITIPTARAEPRE
VYEASASPSLEPSQYPLGAARAQLHQNYIVAQTEDGLVIVDQHAAHERLVFEEMRNALHSRRPPSQVLLIPEIIDLPEED
CDRLMDHAAGFDALGLVIERFGPGAVAVRETPAMLGEVNVQGLVRQLADEIAEWDAASTLANKLEYVAATMACHGSVRSG
RRMRPEEMNALLRQMENTPGSGQCNHGRPTYIELKLSDIERLFGRS

Nucleotide


Download         Length: 1821 bp        

>NTDB_id=752718 A6U93_RS01960 WP_065658275.1 388360..390180(-) (hexB) [Agrobacterium tumefaciens strain 15-1187-1-2a]
ATGGCCATCAAGCAGCTTTCAGAAACCCTCATCAACCAGATCGCCGCCGGCGAGGTCATCGAAAGACCCTCCAGCGCCAC
GAAGGAGCTGGTGGAAAACGCCATCGACGCGGGCGCAACGCGCATCGAGATCGCCACGGCGGGCGGTGGCAAGGGACTGG
TGCGCATCACCGATAACGGCTCCGGCATGTCGCCTGCCGATCTGGAGCTTGCGGTCCGACGCCATTGCACCTCGAAAATA
TCCACCACGCTTGACGATATCCGCACGCTTGGCTTTCGCGGCGAGGCCCTGCCCTCCATCGGCTCGGTTGCCAAGCTTTC
CATCACCAGCCGGCAACACGGCGCAGAACAGGGTTCGGTGATCTCCGTCACCGGCGGCAAAGTCTCCGAGGTCCGGCCCG
CCGCCGCCAATGCCGGCACCATCGTCGAGGTGCGCGACCTGTTTTTCGCGACGCCCGCACGGCTGAAATTCCTGAAGACG
GAGCGAGCGGAGGCAGCCGCCATTACCGAAGTCGTTAAGCGGATGGCAATTGCCTTTCCGCATATCCGCTTCGTGCTGTC
AGGCACCGACCGCTCCACGCTTGAAATCCCCTCCACCGGCGACGATCACCTTGCCCGCATGGCGCAGATTCTCGGTGCCG
AGTTCAAGGACAACGCCATCGAAATCGATGCCGGGCGCGAGGATGTAACGCTCTCCGGTTTTGCCGGCGTGCCAACCTTC
AACCGCGGCAACTCGGCGCATCAATATGTCTTCGTCAACGGTCGCCCGGTGCAGGACAAATTGCTGTTGTCCGCCATTCG
CGGTGCCTATGCCGAAACCGTGCCGCACGGGCGATATCCGGTCGCGGTGCTGTCCCTGACGCTCGATCCCGCCTTTGTCG
ACGTGAACGTGCATCCGGCGAAATCAGATGTGCGCTTTCGCGATCCCGGCCTGGTTCGCGGGCTGATCGTCGGTGCGATC
CGCCAGGCGCTGACCCGCGACGGTGACAGGGCGGCGACGACTGGTGCCAGCCAGATGATGAACGCCTTTCGCCCCGGCTA
CAGCCCGTCCAATCTGCGACCGTCTGCCGCTGCGACATGGTCCGCCGCGGCCTCGCCTTCCCGACCGCTTGCCGTTTCCG
GGAACATGCAATTTGCCGAGGCCGTGCAATCGCGCTTTTCCGACATCACCATCCCGACCGCGCGGGCAGAACCCCGCGAG
GTTTACGAGGCCTCGGCAAGCCCGTCGCTCGAACCGTCACAATATCCGCTCGGCGCCGCGCGGGCGCAGTTGCACCAGAA
TTACATCGTCGCGCAGACGGAAGACGGCCTCGTCATCGTCGACCAGCATGCGGCGCATGAACGGCTCGTGTTTGAGGAAA
TGCGCAATGCGCTGCATTCCAGGCGCCCGCCTTCACAGGTGCTGCTCATTCCTGAGATCATCGACCTTCCCGAAGAGGAT
TGCGACCGGCTGATGGACCATGCGGCTGGTTTCGATGCGCTGGGACTGGTCATCGAGCGTTTCGGGCCGGGGGCGGTCGC
GGTTCGCGAAACGCCGGCGATGCTTGGCGAGGTCAACGTGCAGGGGCTGGTGCGGCAGCTTGCCGACGAGATCGCTGAAT
GGGACGCTGCCTCCACGCTTGCCAACAAGCTGGAATATGTCGCCGCCACCATGGCTTGCCACGGCTCGGTGCGTTCAGGG
CGGCGCATGCGGCCGGAGGAGATGAACGCGCTTTTACGGCAGATGGAAAACACGCCGGGTTCAGGACAGTGCAATCACGG
TCGTCCGACCTATATTGAGCTAAAACTTTCCGATATAGAACGTCTCTTCGGCCGAAGCTGA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(416-562)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(24-122)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(208-324)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AA44F0C8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

34.317

100

0.365