Detailed information NTG0752668

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: QFA72_RS14995
• Genome accession: NZ_CP123780
• Coordinates: 3449408..3450532 (+)
• Length: 374 a.a.
• NCBI ID: WP_189520661.1
• Uniprot ID: A0ABW6EGR2
• Organism: Streptomyces sp. SH5
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3444408..3455532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QFA72_RS14980 (QFA72_14980)	-	3444786..3445649 (+)	864	WP_189520663.1	hypothetical protein	-
QFA72_RS14985 (QFA72_14985)	-	3445776..3447722 (-)	1947	WP_280930774.1	hypothetical protein	-
QFA72_RS14990 (QFA72_14990)	radA/sms	3447915..3449327 (+)	1413	WP_065485347.1	DNA repair protein RadA	Machinery gene
QFA72_RS14995 (QFA72_14995)	disA	3449408..3450532 (+)	1125	WP_189520661.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
QFA72_RS15000 (QFA72_15000)	-	3450891..3451640 (-)	750	WP_280930775.1	hypothetical protein	-
QFA72_RS15005 (QFA72_15005)	-	3451946..3452860 (+)	915	WP_280930776.1	A/G-specific adenine glycosylase	-
QFA72_RS15010 (QFA72_15010)	-	3453030..3453692 (+)	663	WP_280930778.1	SigE family RNA polymerase sigma factor	-
QFA72_RS15015 (QFA72_15015)	-	3453797..3454453 (+)	657	WP_280930780.1	hypothetical protein	-
QFA72_RS15020 (QFA72_15020)	cseB	3454488..3455201 (+)	714	WP_069744685.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40398.32 Da
• Isoelectric Point: 4.9406

>NTDB_id=752668 QFA72_RS14995 WP_189520661.1 3449408..3450532(+) (disA) [Streptomyces sp. SH5]
MAANDRATTPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDRTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVGEALTELDSLSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=752668 QFA72_RS14995 WP_189520661.1 3449408..3450532(+) (disA) [Streptomyces sp. SH5]
GTGGCAGCCAACGACCGGGCGACGACGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAGGCGCTGATGCGCGCCTCGCT
GAGCGCGGTCGCGCCCGGTATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAATACCGGCGGCCTGATCGTGC
TGGGCATGGACCGGACCGTCGAGTCGATGTGCACCGGCGGATTCGTGCTGGACGTGGAGTTCACGGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGGGCGCTGATCCTCGACAAGGACATGACCAAGATCCTGCGGGCCGGCGTGCAGCTGGTCCC
GGACGCCTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGCTTCCCCG
TGGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTGTCGCGGGCCAATCAGGCGCTCGCCACGCTGGAGCGGTACAAGCTCCGCCTCGACGAGGTCGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGGCTGGAGATGGTGCGGCGGATCG
CGACGGAGATCGCGGAGTACGTGGTCGAGCTCGGCACCGACGGACGGCTCCTCTCGCTCCAGCTGGACGAGCTGATCGCC
GGGGTGGAGCCGGAGCGGGAGCTGGTCGTCCGGGATTACGTCCCCGAACCGACGGCGAAACGGTCGCGCACGGTGGGCGA
GGCGCTGACCGAGCTGGACTCCCTGAGCCACACGGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGCTACAGCG
GCTCGCCGGAGACGCTGGACTCGGCGGTGTCCCCGCGGGGCTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGTGGGCTGCAGAAGCTTCTTGCCGCGAGCGTGGACGACCTCCAGACCGTCGA
CGGGGTCGGTGAGGCGCGGGCGCGGAGTGTTCGCGAGGGGCTGTCACGGCTGGCGGAGTCGTCGATCCTGGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436