Detailed information NTG0752650

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NOV96_RS02900
• Genome accession: NZ_CP110141
• Coordinates: 568794..569843 (+)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain WUSS030
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 563794..574843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NOV96_RS02865 (NOV96_02865)	-	564115..565209 (+)	1095	WP_004194740.1	sensor histidine kinase	-
NOV96_RS02870 (NOV96_02870)	-	565206..565808 (+)	603	WP_004194738.1	response regulator transcription factor	-
NOV96_RS02875 (NOV96_02875)	-	566108..566326 (+)	219	WP_004194736.1	YqgQ family protein	-
NOV96_RS02880 (NOV96_02880)	-	566326..566712 (+)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NOV96_RS02885 (NOV96_02885)	-	566769..567491 (+)	723	WP_013730502.1	hypothetical protein	-
NOV96_RS02890 (NOV96_02890)	rsmD	567790..568329 (+)	540	WP_024394248.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NOV96_RS02895 (NOV96_02895)	coaD	568319..568807 (+)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
NOV96_RS02900 (NOV96_02900)	sepM	568794..569843 (+)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
NOV96_RS02905 (NOV96_02905)	-	570031..570672 (+)	642	WP_004194595.1	YutD-like domain-containing protein	-
NOV96_RS02910 (NOV96_02910)	rlmN	570681..571793 (+)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NOV96_RS02915 (NOV96_02915)	-	571790..572317 (+)	528	WP_004194600.1	VanZ family protein	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=752650 NOV96_RS02900 WP_004194592.1 568794..569843(+) (sepM) [Streptococcus suis strain WUSS030]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=752650 NOV96_RS02900 WP_004194592.1 568794..569843(+) (sepM) [Streptococcus suis strain WUSS030]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605