Detailed information NTG0751104

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: OHM48_RS07935
• Genome accession: NZ_CP109942
• Coordinates: 1596611..1597660 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain ID35541
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1591611..1602660

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHM48_RS07915 (OHM48_07915)	nadE	1592017..1592841 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
OHM48_RS07920 (OHM48_07920)	-	1594137..1594664 (-)	528	WP_012027591.1	VanZ family protein	-
OHM48_RS07925 (OHM48_07925)	rlmN	1594661..1595773 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
OHM48_RS07930 (OHM48_07930)	-	1595782..1596423 (-)	642	WP_204108405.1	YutD-like domain-containing protein	-
OHM48_RS07935 (OHM48_07935)	sepM	1596611..1597660 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
OHM48_RS07940 (OHM48_07940)	coaD	1597647..1598135 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
OHM48_RS07945 (OHM48_07945)	rsmD	1598125..1598664 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
OHM48_RS07950 (OHM48_07950)	-	1598972..1599694 (-)	723	WP_012027598.1	lipoprotein	-
OHM48_RS07955 (OHM48_07955)	-	1599751..1600137 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
OHM48_RS07960 (OHM48_07960)	-	1600137..1600355 (-)	219	WP_004194736.1	YqgQ family protein	-
OHM48_RS07965 (OHM48_07965)	-	1600663..1601265 (-)	603	WP_012027601.1	response regulator transcription factor	-
OHM48_RS07970 (OHM48_07970)	-	1601262..1602356 (-)	1095	WP_024383662.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=751104 OHM48_RS07935 WP_012775295.1 1596611..1597660(-) (sepM) [Streptococcus suis strain ID35541]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=751104 OHM48_RS07935 WP_012775295.1 1596611..1597660(-) (sepM) [Streptococcus suis strain ID35541]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605