Detailed information NTG0750943

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: OHM47_RS07140
• Genome accession: NZ_CP109939
• Coordinates: 1393062..1394111 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain ID36054
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1388062..1399111

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHM47_RS07120 (OHM47_07120)	nadE	1388671..1389495 (+)	825	WP_024413453.1	ammonia-dependent NAD(+) synthetase	-
OHM47_RS07125 (OHM47_07125)	-	1390588..1391115 (-)	528	WP_002942846.1	VanZ family protein	-
OHM47_RS07130 (OHM47_07130)	rlmN	1391112..1392224 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
OHM47_RS07135 (OHM47_07135)	-	1392233..1392874 (-)	642	WP_014638483.1	YutD-like domain-containing protein	-
OHM47_RS07140 (OHM47_07140)	sepM	1393062..1394111 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
OHM47_RS07145 (OHM47_07145)	coaD	1394098..1394586 (-)	489	WP_015647233.1	pantetheine-phosphate adenylyltransferase	-
OHM47_RS07150 (OHM47_07150)	rsmD	1394576..1395115 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
OHM47_RS07155 (OHM47_07155)	-	1395422..1396144 (-)	723	WP_024417717.1	hypothetical protein	-
OHM47_RS07160 (OHM47_07160)	-	1396201..1396587 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
OHM47_RS07165 (OHM47_07165)	-	1396587..1396805 (-)	219	WP_004194736.1	YqgQ family protein	-
OHM47_RS07170 (OHM47_07170)	-	1397113..1397715 (-)	603	WP_024417718.1	response regulator transcription factor	-
OHM47_RS07175 (OHM47_07175)	-	1397712..1398806 (-)	1095	WP_024415248.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=750943 OHM47_RS07140 WP_012775295.1 1393062..1394111(-) (sepM) [Streptococcus suis strain ID36054]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=750943 OHM47_RS07140 WP_012775295.1 1393062..1394111(-) (sepM) [Streptococcus suis strain ID36054]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605