Detailed information NTG0750800

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NT398_RS00460
• Genome accession: NZ_CP109933
• Coordinates: 82002..83045 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SASWT1215
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 77002..88045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NT398_RS00430 (NT398_00430)	-	77428..77538 (+)	111	WP_001790257.1	hypothetical protein	-
NT398_RS00435 (NT398_00435)	-	77567..77980 (+)	414	WP_001557448.1	hypothetical protein	-
NT398_RS00440 (NT398_00440)	-	78411..79397 (-)	987	WP_000999717.1	aromatic acid exporter family protein	-
NT398_RS00445 (NT398_00445)	map	79928..80686 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NT398_RS00450 (NT398_00450)	-	80903..81289 (+)	387	WP_001110179.1	hypothetical protein	-
NT398_RS00455 (NT398_00455)	liaF	81304..82005 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NT398_RS00460 (NT398_00460)	vraS	82002..83045 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NT398_RS00465 (NT398_00465)	vraR	83035..83664 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
NT398_RS00470 (NT398_00470)	-	83777..84994 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
NT398_RS00475 (NT398_00475)	-	85272..85547 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
NT398_RS00480 (NT398_00480)	-	85554..86018 (-)	465	WP_042109418.1	low molecular weight protein-tyrosine-phosphatase	-
NT398_RS00485 (NT398_00485)	-	86165..86365 (+)	201	WP_000180460.1	DUF1128 family protein	-
NT398_RS00490 (NT398_00490)	-	86368..87624 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=750800 NT398_RS00460 WP_001017131.1 82002..83045(+) (vraS) [Staphylococcus aureus strain SASWT1215]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=750800 NT398_RS00460 WP_001017131.1 82002..83045(+) (vraS) [Staphylococcus aureus strain SASWT1215]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1