Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAO56_RS05850 Genome accession   NZ_CP123156
Coordinates   1178260..1180041 (+) Length   593 a.a.
NCBI ID   WP_000390521.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GE-MRSA16     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1173260..1185041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO56_RS05830 (QAO56_05815) polX 1173378..1175090 (+) 1713 WP_000161953.1 DNA polymerase/3'-5' exonuclease PolX -
  QAO56_RS05835 (QAO56_05820) mutS/mutS2 1175100..1177448 (+) 2349 WP_001249280.1 endonuclease MutS2 Machinery gene
  QAO56_RS05840 (QAO56_05825) trxA 1177621..1177935 (+) 315 WP_001018928.1 thioredoxin -
  QAO56_RS05845 (QAO56_05830) - 1177998..1178069 (-) 72 WP_223200532.1 hypothetical protein -
  QAO56_RS05850 (QAO56_05835) uvrC 1178260..1180041 (+) 1782 WP_000390521.1 excinuclease ABC subunit UvrC Machinery gene
  QAO56_RS05855 (QAO56_05840) - 1180365..1180979 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  QAO56_RS05860 (QAO56_05845) sdhA 1181031..1182797 (+) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  QAO56_RS05865 (QAO56_05850) sdhB 1182797..1183612 (+) 816 WP_000132057.1 succinate dehydrogenase iron-sulfur subunit -
  QAO56_RS05870 (QAO56_05855) racE 1183852..1184652 (+) 801 WP_001039660.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68653.34 Da        Isoelectric Point: 9.7443

>NTDB_id=748665 QAO56_RS05850 WP_000390521.1 1178260..1180041(+) (uvrC) [Staphylococcus aureus strain GE-MRSA16]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRHFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKEMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFIDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNLGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=748665 QAO56_RS05850 WP_000390521.1 1178260..1180041(+) (uvrC) [Staphylococcus aureus strain GE-MRSA16]
TTGGAAGATTATAAACAACGAATTAAAAATAAATTAAATGTTGTACCTATGGAACCGGGTTGCTATTTAATGAAAGACCG
CAATGATCAAGTGATATATGTTGGGAAAGCTAAAAAATTAAGAAATCGATTACGATCATATTTTACGGGCGCACACGATG
CTAAAACAACGAGACTTGTTGGAGAAATACGGCATTTTGAATTTATTGTCACATCTAGTGAAACAGAGTCATTATTACTT
GAATTAAATTTGATCAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGCTGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAACGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTGCCGCGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGAGATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCAATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTATCGACGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGCCGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACCGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATTTAGGTATTCCTGAAAACGTTGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565