Detailed information NTG0748651

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: OF801_RS02985
• Genome accession: NZ_CP109635
• Coordinates: 581668..583158 (+)
• Length: 496 a.a.
• NCBI ID: WP_014024351.1
• Uniprot ID: A0AA46TWW1
• Organism: Lactococcus garvieae strain Alexii-11_2
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 576668..588158

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OF801_RS02960 (OF801_02960)	pfkB	576815..577741 (+)	927	WP_004259111.1	1-phosphofructokinase	-
OF801_RS02965 (OF801_02965)	-	577756..579660 (+)	1905	WP_014024348.1	fructose-specific PTS transporter subunit EIIC	-
OF801_RS02970 (OF801_02970)	-	579772..580014 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
OF801_RS02975 (OF801_02975)	-	580231..580782 (+)	552	WP_165705968.1	YceD family protein	-
OF801_RS02980 (OF801_02980)	covR	580884..581579 (+)	696	WP_004259096.1	response regulator transcription factor	Regulator
OF801_RS02985 (OF801_02985)	covS	581668..583158 (+)	1491	WP_014024351.1	HAMP domain-containing histidine kinase	Regulator
OF801_RS02990 (OF801_02990)	-	583555..585126 (+)	1572	WP_004259090.1	ABC transporter permease subunit	-
OF801_RS02995 (OF801_02995)	-	585127..585864 (+)	738	WP_014024353.1	amino acid ABC transporter ATP-binding protein	-
OF801_RS03000 (OF801_03000)	murD	586003..587364 (+)	1362	WP_264308520.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56753.73 Da
• Isoelectric Point: 5.1966

>NTDB_id=748651 OF801_RS02985 WP_014024351.1 581668..583158(+) (covS) [Lactococcus garvieae strain Alexii-11_2]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=748651 OF801_RS02985 WP_014024351.1 581668..583158(+) (covS) [Lactococcus garvieae strain Alexii-11_2]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTATCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACATTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGTAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCGC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTAATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTAGAACGGTTGCACGATGCAATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTTAGTCATGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATCGATTTTCAAGATGAAGATCTTATCTG
TGATCCGACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATTCATGCTGATTTAAGCTTAACTGTTGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTATGATGGGGATGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• ArlS sensor domain (ArlS_N) (52-190)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• HAMP domain (HAMP) (214-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.936	100	0.56