Detailed information NTG0748640

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OF801_RS02260
• Genome accession: NZ_CP109635
• Coordinates: 426664..429114 (+)
• Length: 816 a.a.
• NCBI ID: WP_264308690.1
• Uniprot ID: A0AA46TYG5
• Organism: Lactococcus garvieae strain Alexii-11_2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 421664..434114

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OF801_RS02235 (OF801_02235)	-	422571..423083 (+)	513	WP_003134000.1	adenine phosphoribosyltransferase	-
OF801_RS02240 (OF801_02240)	rpoE	423221..423781 (+)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
OF801_RS02245 (OF801_02245)	mltG	423887..425602 (+)	1716	WP_264308469.1	endolytic transglycosylase MltG	-
OF801_RS02250 (OF801_02250)	greA	425627..426100 (+)	474	WP_003134005.1	transcription elongation factor GreA	-
OF801_RS02255 (OF801_02255)	-	426222..426674 (+)	453	WP_003134006.1	CtsR family transcriptional regulator	-
OF801_RS02260 (OF801_02260)	clpC	426664..429114 (+)	2451	WP_264308690.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
OF801_RS02265 (OF801_02265)	raiA	429238..429795 (+)	558	WP_003134010.1	ribosome-associated translation inhibitor RaiA	-
OF801_RS02270 (OF801_02270)	pflB	430043..432376 (+)	2334	WP_003134012.1	formate C-acetyltransferase	-
OF801_RS02275 (OF801_02275)	coaE	432607..433212 (+)	606	WP_264308470.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91061.25 Da
• Isoelectric Point: 6.0523

>NTDB_id=748640 OF801_RS02260 WP_264308690.1 426664..429114(+) (clpC) [Lactococcus garvieae strain Alexii-11_2]
MKFNEKDFTPQVVRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKAKKSDI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEKETVAILQGLKEKFEAYHAVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELKLQQAVVALDIVEAQGIEKDIERLTHKIDNFTVSENDNPLV
EESDIYAVVSNLTGIPLQQMTKTESERLINLEKELHQRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNITVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGDIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=748640 OF801_RS02260 WP_264308690.1 426664..429114(+) (clpC) [Lactococcus garvieae strain Alexii-11_2]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTTGTTAGAGTGCTTGAGAAGTCTGTCGACTATGCGCATAAGTTTAA
CTACGCTTGGGTAGAAAGCTCACACCTATTGGCTGCCTTAGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAGATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTGAAGGCAAAAAAATCAGACATA
AAGCTTAGCCCAAGAGTTGAAACGATTATTGAGCAAGCCCGAGCATTGGCACAAAATAACGATAAAAACCGTATTGGGAC
AGAACATCTCTTGTATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAAACATTAATATCG
TTAACCTCCGTAAAAAGTTAGAGCAAAAAGCATATTTACGAGTGCCAGAACGCCGTAAAGCGGTGACCCCAGCTTCGAAA
AGAAACCTGTCGGGGAAGGTGTCCGAAACAACAACAACACCTACTTTAGATACAGTCTCGACAGATTTGACAAAAGCAGC
GCGTGAAGGCAAGCTTGATCCAATGATTGGGAGAGAGCGTGAAGTCGAACGTCTTATCCATATTTTGAGTCGCCGAACAA
AGAATAATCCCGTTCTTGTTGGTGAACCAGGCGTTGGTAAGTCAGCGATTATTGAAGGCTTTGCGACACGTGTGGCTGCA
GGAAATGTTCCTGTAGGTTTACGCGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTCGTAGCGGGGACGAAGTTCCG
TGGTGAATTTGAAGATCGTTTGACAGCTATTGTGGATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACTATTATTGGTGCTGGGGGAGGCATGGACTCTGTCAATGATGCCTCAAACATTTTAAAACCCGCATTAGCACGT
GGCGAGTTTCAACTTATTGGAGCTACTACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCTCTGGAGCGCCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAAAAGAAACGGTTGCGATTTTACAAGGCTTGAAAGAAAAATTTGAAG
CTTACCATGCGGTTAAATTTGAAGAAGGGGCTTTGGAGCGTGCCGTTAGCTTGAGTAATCGCTACATGCCAAGTCGTCGT
CTGCCAGATAAAGCCATTGATCTTCTTGATGAAGCAGCGGCCAAAGTTAAAATCACGAGTAAAACAAATTACACCAAGCT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAGCTGAAATTACAACAAGCAGTTGTTGCTCTTGATATTGTTGAAGCAC
AAGGAATTGAAAAAGATATTGAAAGATTAACACACAAAATTGATAATTTTACAGTCTCGGAAAATGATAATCCTTTGGTT
GAAGAAAGCGATATTTATGCTGTTGTTTCTAACCTTACAGGAATTCCGCTCCAACAAATGACGAAAACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATCAACGTGTGGTCGGACAGGAAGAAGCGATTTCGGCTGTTTCTCGTGCTATAA
GACGTGCGCGTTCAGGTATTGCTGATACGAGACGTCCTCTGGGCTCATTTATGTTCCTTGGTCCGACAGGGGTGGGGAAA
ACAGAGCTTGCTAAAGCTTTAGCGGAAAGTGTCTTTGGGAGTGAAGAGAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCAGGGTATGTAGGTTACGACGAAGGGGGACAATTGACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTTGAAAAAGCCCATCCTGACATTTTCAATATCATGTTG
CAAATTTTGGATGACGGTTTCGTTACAGATACCAAAGGGCGGAAAGTTGATTTCAGAAATACAATCATTATTATGACATC
TAACTTAGGCGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACAGATTATGCAGCCA
TGAAAGCAAGAATCATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTTAACCGTATCGATGAAACCATCGTTTTC
CATTCACTGACTGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGCAAATCTCTTGTATCACGTTTGAAAGATCAAAA
TATCACAGTGAAATTTACCCCTGCTGCCTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAGTATGGTGCACGTCCGT
TGCGTAAAGCGCTACAACGGGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCAGGCGACATTCATCCGGGGGATACG
ATTTCTATTGGATCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.552	99.877	0.705
clpC	Streptococcus thermophilus LMG 18311	49.698	100	0.504
clpC	Streptococcus thermophilus LMD-9	49.698	100	0.504
clpC	Streptococcus pneumoniae TIGR4	49.274	100	0.499
clpC	Streptococcus pneumoniae Rx1	49.153	100	0.498
clpC	Streptococcus pneumoniae D39	49.153	100	0.498
clpC	Streptococcus mutans UA159	47.488	100	0.487
clpC	Bacillus subtilis subsp. subtilis str. 168	48.31	97.917	0.473
clpE	Streptococcus mutans UA159	46.875	78.431	0.368