Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   QAO49_RS14355 Genome accession   NZ_CP123151
Coordinates   2855146..2855853 (-) Length   235 a.a.
NCBI ID   WP_000094093.1    Uniprot ID   A0A1D4DWM6
Organism   Staphylococcus aureus strain GE-MRSA18     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2850146..2860853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO49_RS14320 (QAO49_14335) lukG 2850414..2851430 (+) 1017 WP_000595324.1 bi-component leukocidin LukGH subunit G -
  QAO49_RS14325 (QAO49_14340) sph 2851653..2852494 (-) 842 Protein_2782 sphingomyelin phosphodiesterase -
  QAO49_RS14330 (QAO49_14345) - 2852551..2853588 (-) 1038 WP_000857198.1 tyrosine-type recombinase/integrase -
  QAO49_RS14335 (QAO49_14350) - 2853761..2854300 (-) 540 WP_000391618.1 type II toxin-antitoxin system PemK/MazF family toxin -
  QAO49_RS14340 (QAO49_14355) - 2854440..2854607 (-) 168 WP_000705238.1 hypothetical protein -
  QAO49_RS14345 (QAO49_14360) - 2854807..2854992 (-) 186 WP_001089804.1 hypothetical protein -
  QAO49_RS14350 (QAO49_14365) - 2854979..2855134 (-) 156 WP_001049399.1 hypothetical protein -
  QAO49_RS14355 (QAO49_14370) irvR 2855146..2855853 (-) 708 WP_000094093.1 helix-turn-helix domain-containing protein Regulator
  QAO49_RS14360 (QAO49_14375) - 2856024..2856263 (+) 240 WP_000548578.1 helix-turn-helix transcriptional regulator -
  QAO49_RS14365 (QAO49_14380) - 2856276..2856536 (+) 261 WP_000435341.1 transcriptional regulator -
  QAO49_RS14370 (QAO49_14385) - 2856560..2857099 (-) 540 WP_000351243.1 hypothetical protein -
  QAO49_RS14375 (QAO49_14390) - 2857156..2857908 (+) 753 WP_001148618.1 phage antirepressor KilAC domain-containing protein -
  QAO49_RS14380 (QAO49_14395) - 2857925..2858119 (+) 195 WP_000388066.1 hypothetical protein -
  QAO49_RS14385 (QAO49_14400) - 2858150..2858290 (+) 141 WP_000939496.1 hypothetical protein -
  QAO49_RS14390 (QAO49_14405) - 2858305..2858937 (-) 633 WP_000275058.1 hypothetical protein -
  QAO49_RS14395 (QAO49_14410) - 2858996..2859316 (+) 321 WP_001120197.1 DUF771 domain-containing protein -
  QAO49_RS14400 (QAO49_14415) - 2859313..2859474 (+) 162 WP_000066020.1 DUF1270 domain-containing protein -
  QAO49_RS14405 (QAO49_14420) - 2859567..2859827 (+) 261 WP_000291489.1 DUF1108 family protein -
  QAO49_RS14410 (QAO49_14425) - 2859836..2860099 (+) 264 WP_001205732.1 hypothetical protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26769.35 Da        Isoelectric Point: 5.4082

>NTDB_id=748544 QAO49_RS14355 WP_000094093.1 2855146..2855853(-) (irvR) [Staphylococcus aureus strain GE-MRSA18]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=748544 QAO49_RS14355 WP_000094093.1 2855146..2855853(-) (irvR) [Staphylococcus aureus strain GE-MRSA18]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(123-234)

Helix-turn-helix (HTH_3)

(8-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1D4DWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

30.769

100

0.374