Detailed information NTG0074821

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: F6Y14_RS11115
• Genome accession: NZ_AP020322
• Coordinates: 2198510..2199397 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain KUH180129
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2193510..2204397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6Y14_RS11085 (KUH180129_2086)	-	2194242..2195003 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
F6Y14_RS11090 (KUH180129_2087)	-	2195248..2195703 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
F6Y14_RS15085 (KUH180129_2088)	-	2195825..2195926 (+)	102	WP_000731976.1	SE2200 family small protein	-
F6Y14_RS11100 (KUH180129_2089)	-	2195986..2197410 (-)	1425	WP_000953755.1	alkaline phosphatase	-
F6Y14_RS11105 (KUH180129_2090)	-	2197608..2197808 (+)	201	WP_000604730.1	hypothetical protein	-
F6Y14_RS11110 (KUH180129_2091)	braR	2197834..2198499 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
F6Y14_RS11115 (KUH180129_2092)	braS	2198510..2199397 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
F6Y14_RS11120 (KUH180129_2093)	-	2199505..2200260 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
F6Y14_RS11125 (KUH180129_2094)	-	2200257..2202257 (+)	2001	WP_000776751.1	ABC transporter permease	-
F6Y14_RS11130	-	2202916..2203029 (+)	114	Protein_2118	hypothetical protein	-
F6Y14_RS11140 (KUH180129_2095)	-	2203411..2203671 (+)	261	WP_001791974.1	hypothetical protein	-
F6Y14_RS11145 (KUH180129_2096)	-	2203681..2204178 (+)	498	WP_001065268.1	glutathione peroxidase	-
F6Y14_RS11150	-	2204286..2204378 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=74821 F6Y14_RS11115 WP_000143425.1 2198510..2199397(+) (braS) [Staphylococcus aureus strain KUH180129]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=74821 F6Y14_RS11115 WP_000143425.1 2198510..2199397(+) (braS) [Staphylococcus aureus strain KUH180129]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1