Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   QAY82_RS06515 Genome accession   NZ_CP123137
Coordinates   1313328..1314002 (-) Length   224 a.a.
NCBI ID   WP_001166500.1    Uniprot ID   Q99VW2
Organism   Staphylococcus aureus strain GE-MRSA23     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1308328..1319002
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAY82_RS06500 (QAY82_06495) vraG 1309512..1311401 (-) 1890 WP_110417907.1 ABC transporter permease VraG -
  QAY82_RS06505 (QAY82_06500) vraF 1311391..1312151 (-) 761 Protein_1255 ABC transporter ATP-binding protein VraF -
  QAY82_RS06510 (QAY82_06505) graS 1312295..1313335 (-) 1041 WP_001061264.1 histidine kinase GraS/ApsS -
  QAY82_RS06515 (QAY82_06510) braR 1313328..1314002 (-) 675 WP_001166500.1 response regulator transcription factor GraR/ApsR Regulator
  QAY82_RS06520 (QAY82_06515) graX 1314018..1314941 (-) 924 WP_000802953.1 auxiliary protein GraX/ApsX -
  QAY82_RS06525 (QAY82_06520) - 1315054..1315560 (+) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  QAY82_RS06530 (QAY82_06525) - 1315769..1316197 (-) 429 WP_000198504.1 hypothetical protein -
  QAY82_RS06535 (QAY82_06530) - 1316526..1317569 (-) 1044 WP_001030772.1 alpha/beta hydrolase -
  QAY82_RS06540 (QAY82_06535) - 1317720..1318787 (-) 1068 WP_000980137.1 membrane protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26065.87 Da        Isoelectric Point: 4.3563

>NTDB_id=748078 QAY82_RS06515 WP_001166500.1 1313328..1314002(-) (braR) [Staphylococcus aureus strain GE-MRSA23]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=748078 QAY82_RS06515 WP_001166500.1 1313328..1314002(-) (braR) [Staphylococcus aureus strain GE-MRSA23]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCTTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGACGATACGATTTTTCTATCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(149-221)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q99VW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.455

98.214

0.397