Detailed information NTG0747014

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: QAO52_RS06090
• Genome accession: NZ_CP123108
• Coordinates: 1227656..1228738 (-)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain IT-MSSA49
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1222656..1233738

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO52_RS06070 (QAO52_06065)	-	1223265..1223369 (-)	105	WP_001790092.1	hypothetical protein	-
QAO52_RS06075 (QAO52_06070)	secA	1223411..1225942 (-)	2532	WP_000506531.1	preprotein translocase subunit SecA	-
QAO52_RS06080 (QAO52_06075)	hpf	1226356..1226928 (-)	573	WP_000617735.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
QAO52_RS06085 (QAO52_06080)	-	1226989..1227663 (-)	675	WP_001057965.1	ComF family protein	-
QAO52_RS06090 (QAO52_06085)	comFA	1227656..1228738 (-)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
QAO52_RS06095 (QAO52_06090)	fakB1	1229102..1229968 (-)	867	WP_000686342.1	fatty acid kinase binding subunit FakB1	-
QAO52_RS06100 (QAO52_06095)	-	1230112..1230753 (+)	642	WP_000192947.1	YigZ family protein	-
QAO52_RS06105 (QAO52_06100)	-	1230923..1231978 (-)	1056	WP_000258151.1	glycosyltransferase family 4 protein	-
QAO52_RS06110 (QAO52_06105)	gdpS	1232296..1233366 (+)	1071	WP_000460983.1	GGDEF domain-containing protein GdpS	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=747014 QAO52_RS06090 WP_001548033.1 1227656..1228738(-) (comFA) [Staphylococcus aureus strain IT-MSSA49]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=747014 QAO52_RS06090 WP_001548033.1 1227656..1228738(-) (comFA) [Staphylococcus aureus strain IT-MSSA49]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATTTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGGGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367