Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   F6Y18_RS13605 Genome accession   NZ_AP020316
Coordinates   2713528..2714244 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain KUH140331     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2708528..2719244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6Y18_RS13585 (KUH140331_2531) - 2709620..2710570 (+) 951 WP_000790326.1 LacI family DNA-binding transcriptional regulator -
  F6Y18_RS13590 (KUH140331_2532) - 2710719..2712203 (+) 1485 WP_000141435.1 sucrose-6-phosphate hydrolase -
  F6Y18_RS13595 (KUH140331_2533) - 2712200..2713159 (+) 960 WP_001253302.1 carbohydrate kinase family protein -
  F6Y18_RS13600 - 2713347..2713456 (-) 110 Protein_2587 hypothetical protein -
  F6Y18_RS13605 (KUH140331_2534) agrA 2713528..2714244 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  F6Y18_RS13610 (KUH140331_2535) agrC 2714263..2715555 (-) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  F6Y18_RS13615 (KUH140331_2536) agrD 2715580..2715720 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  F6Y18_RS13620 (KUH140331_2537) agrB 2715717..2716286 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  F6Y18_RS14065 hld 2716576..2716656 (+) 81 WP_000046022.1 delta-hemolysin -
  F6Y18_RS13630 (KUH140331_2539) - 2717256..2718041 (-) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  F6Y18_RS13635 (KUH140331_2540) - 2718402..2719028 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=74696 F6Y18_RS13605 WP_000688498.1 2713528..2714244(-) (agrA) [Staphylococcus aureus strain KUH140331]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=74696 F6Y18_RS13605 WP_000688498.1 2713528..2714244(-) (agrA) [Staphylococcus aureus strain KUH140331]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment