Detailed information NTG0746685

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: QAY70_RS13590
• Genome accession: NZ_CP123099
• Coordinates: 2749301..2750014 (-)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain IT-MSSA55
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2744301..2755014

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY70_RS13560 (QAY70_13550)	sph	2745079..2745903 (-)	825	Protein_2629	sphingomyelin phosphodiesterase	-
QAY70_RS13565 (QAY70_13555)	-	2745960..2746997 (-)	1038	WP_000857191.1	tyrosine-type recombinase/integrase	-
QAY70_RS13570 (QAY70_13560)	-	2747056..2747520 (-)	465	WP_000825947.1	hypothetical protein	-
QAY70_RS13575 (QAY70_13565)	-	2747620..2747802 (-)	183	WP_000705248.1	hypothetical protein	-
QAY70_RS13580 (QAY70_13570)	-	2748006..2748347 (-)	342	WP_000591749.1	hypothetical protein	-
QAY70_RS13585 (QAY70_13575)	-	2748353..2749285 (-)	933	WP_000759682.1	exonuclease domain-containing protein	-
QAY70_RS13590 (QAY70_13580)	irvR	2749301..2750014 (-)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
QAY70_RS13595 (QAY70_13585)	-	2749977..2750150 (+)	174	WP_001801500.1	hypothetical protein	-
QAY70_RS13600 (QAY70_13590)	-	2750147..2750410 (+)	264	WP_000854073.1	helix-turn-helix transcriptional regulator	-
QAY70_RS13605 (QAY70_13595)	-	2750426..2750623 (+)	198	WP_001148862.1	hypothetical protein	-
QAY70_RS13610 (QAY70_13600)	-	2750610..2750990 (-)	381	WP_000762519.1	DUF2513 domain-containing protein	-
QAY70_RS13615 (QAY70_13605)	-	2751045..2751368 (+)	324	WP_001120201.1	DUF771 domain-containing protein	-
QAY70_RS13620 (QAY70_13610)	-	2751365..2751526 (+)	162	WP_000048129.1	DUF1270 family protein	-
QAY70_RS13625 (QAY70_13615)	-	2751621..2751923 (+)	303	WP_000165371.1	DUF2482 family protein	-
QAY70_RS13630 (QAY70_13620)	-	2751928..2752188 (+)	261	WP_000291510.1	DUF1108 family protein	-
QAY70_RS13635 (QAY70_13625)	-	2752197..2752460 (+)	264	WP_001205732.1	hypothetical protein	-
QAY70_RS13640 (QAY70_13630)	-	2752469..2754412 (+)	1944	WP_000700555.1	AAA family ATPase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=746685 QAY70_RS13590 WP_001031454.1 2749301..2750014(-) (irvR) [Staphylococcus aureus strain IT-MSSA55]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=746685 QAY70_RS13590 WP_001031454.1 2749301..2750014(-) (irvR) [Staphylococcus aureus strain IT-MSSA55]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401