Detailed information NTG0746657

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: QAY70_RS06145
• Genome accession: NZ_CP123099
• Coordinates: 1235303..1236385 (-)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain IT-MSSA55
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1230303..1241385

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY70_RS06125 (QAY70_06120)	-	1230912..1231016 (-)	105	WP_001790092.1	hypothetical protein	-
QAY70_RS06130 (QAY70_06125)	secA	1231058..1233589 (-)	2532	WP_000506531.1	preprotein translocase subunit SecA	-
QAY70_RS06135 (QAY70_06130)	hpf	1234003..1234575 (-)	573	WP_000617735.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
QAY70_RS06140 (QAY70_06135)	-	1234636..1235310 (-)	675	WP_001057965.1	ComF family protein	-
QAY70_RS06145 (QAY70_06140)	comFA	1235303..1236385 (-)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
QAY70_RS06150 (QAY70_06145)	fakB1	1236749..1237615 (-)	867	WP_000686343.1	fatty acid kinase binding subunit FakB1	-
QAY70_RS06155 (QAY70_06150)	-	1237759..1238400 (+)	642	WP_000192949.1	YigZ family protein	-
QAY70_RS06160 (QAY70_06155)	-	1238565..1239620 (-)	1056	WP_000258150.1	glycosyltransferase family 4 protein	-
QAY70_RS06165 (QAY70_06160)	gdpS	1239938..1241008 (+)	1071	WP_000460983.1	GGDEF domain-containing protein GdpS	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=746657 QAY70_RS06145 WP_001548033.1 1235303..1236385(-) (comFA) [Staphylococcus aureus strain IT-MSSA55]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=746657 QAY70_RS06145 WP_001548033.1 1235303..1236385(-) (comFA) [Staphylococcus aureus strain IT-MSSA55]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATCTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTCCATGAAGGAGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367