Detailed information NTG0074583

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: K6K00_RS00525
• Genome accession: NZ_AP024628
• Coordinates: 101212..102294 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain BEST3145
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 96212..107294

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6K00_RS00510 (BsBEST3145_00850)	mcsB	96220..97311 (+)	1092	WP_003235007.1	protein arginine kinase	-
K6K00_RS00515 (BsBEST3145_00860)	clpC	97308..99740 (+)	2433	WP_003235011.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
K6K00_RS00520 (BsBEST3145_00870)	radA/sms	99832..101208 (+)	1377	WP_004399687.1	DNA repair protein RadA	Machinery gene
K6K00_RS00525 (BsBEST3145_00880)	disA	101212..102294 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
K6K00_RS00530 (BsBEST3145_00890)	yacL	102410..103510 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
K6K00_RS00535 (BsBEST3145_00900)	ispD	103525..104223 (+)	699	WP_003235019.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
K6K00_RS00540 (BsBEST3145_00910)	ispF	104216..104692 (+)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
K6K00_RS00545 (BsBEST3145_00920)	gltX	104783..106234 (+)	1452	WP_004399675.1	glutamate--tRNA ligase	-
K6K00_RS00550 (BsBEST3145_00930)	cysE	106536..107189 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=74583 K6K00_RS00525 WP_003225736.1 101212..102294(+) (disA) [Bacillus subtilis strain BEST3145]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=74583 K6K00_RS00525 WP_003225736.1 101212..102294(+) (disA) [Bacillus subtilis strain BEST3145]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCTGGTCAAAAGATCCTATACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCCATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1