Detailed information NTG0744580

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: QAD58_RS06730
• Genome accession: NZ_CP122956
• Coordinates: 1393323..1394210 (-)
• Length: 295 a.a.
• NCBI ID: WP_350318910.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain BT112
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1388323..1399210

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAD58_RS06690 (QAD58_06695)	infC	1388471..1389082 (+)	612	WP_000089218.1	translation initiation factor IF-3	-
QAD58_RS06695 (QAD58_06700)	rpmI	1389063..1389257 (+)	195	WP_001125542.1	50S ribosomal protein L35	-
QAD58_RS06700 (QAD58_06705)	rplT	1389352..1389702 (+)	351	WP_286448257.1	50S ribosomal protein L20	-
QAD58_RS06705 (QAD58_06710)	-	1389902..1390762 (+)	861	WP_000750190.1	outer membrane protein	-
QAD58_RS06710 (QAD58_06715)	-	1391117..1391305 (+)	189	Protein_1311	DUF1104 domain-containing protein	-
QAD58_RS07805	-	1391268..1392901 (-)	1634	Protein_1312	type IA DNA topoisomerase	-
QAD58_RS06725 (QAD58_06730)	comB4	1392904..1393329 (-)	426	WP_286448259.1	type IV secretory system conjugative DNA transfer family protein	Machinery gene
QAD58_RS06730 (QAD58_06735)	comB4	1393323..1394210 (-)	888	WP_350318910.1	DUF87 domain-containing protein	Machinery gene
QAD58_RS06735 (QAD58_06740)	-	1394217..1395333 (-)	1117	Protein_1315	hypothetical protein	-
QAD58_RS06740 (QAD58_06745)	comB3	1395326..1395592 (-)	267	WP_128039100.1	virB3 type IV secretion protein	Machinery gene
QAD58_RS06745 (QAD58_06750)	-	1395593..1395895 (-)	303	WP_350318897.1	virB2 type IV secretion protein	-
QAD58_RS06750 (QAD58_06755)	-	1395892..1397414 (-)	1523	Protein_1318	hypothetical protein	-
QAD58_RS06755 (QAD58_06760)	-	1397421..1397714 (-)	294	WP_286448263.1	hypothetical protein	-
QAD58_RS06760 (QAD58_06765)	-	1397734..1398513 (-)	780	WP_286448264.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34348.57 Da
• Isoelectric Point: 8.6512

>NTDB_id=744580 QAD58_RS06730 WP_350318910.1 1393323..1394210(-) (comB4) [Helicobacter pylori strain BT112]
MLPMFFSFFPNRNRLNFRKRLLSSQNIASLIILVILEKQNCGFSRNSWGDRHLTIFRNQDKSPYLFNFHVYEAKRKNDMV
SGHTIIFGGTGAGKTTLIEFLITNCFKYEDLSILALDRNNGMRVMTEFLDGQYNDSNDFYINPFSLKDTSANCTFLVSWL
AFMLNIDEDTKDEKEKKTLSALFKTIRVCYNNITKQGGAIFKLRDFKDTLERDYSDSKDILEKESSKDLYKHSTDCLDFA
KKLSVIDMDALSSNKKDFNLAVLYLFYKVMNRAKLENKPFYIFIDEALLLKILSC

Nucleotide

• Length: 888 bp

>NTDB_id=744580 QAD58_RS06730 WP_350318910.1 1393323..1394210(-) (comB4) [Helicobacter pylori strain BT112]
ATGTTGCCTATGTTTTTTAGCTTTTTCCCCAATCGTAATCGCTTGAATTTTAGAAAGCGTTTGTTGTCTAGTCAAAATAT
TGCTTCTTTAATCATATTGGTCATATTGGAAAAACAAAATTGTGGTTTTTCTAGAAATTCATGGGGTGATCGCCATTTAA
CTATTTTTAGAAACCAAGACAAATCGCCTTATTTATTCAATTTCCATGTTTATGAGGCAAAAAGAAAAAATGATATGGTA
TCAGGGCATACCATCATCTTTGGTGGCACAGGGGCTGGTAAAACCACTTTAATTGAATTTTTAATCACCAATTGTTTTAA
GTATGAAGATTTAAGTATTTTGGCTTTAGACAGAAATAATGGCATGCGTGTGATGACTGAGTTCTTAGATGGTCAATACA
ACGATAGCAATGATTTTTACATTAATCCGTTTTCTTTAAAAGATACAAGCGCTAATTGCACCTTTTTAGTGAGTTGGTTG
GCATTCATGCTCAATATTGATGAAGATACTAAAGATGAAAAAGAAAAAAAGACTTTAAGCGCTTTATTCAAAACGATCAG
AGTTTGCTATAACAATATCACAAAACAAGGGGGTGCTATTTTTAAGTTAAGAGATTTTAAAGACACGCTAGAACGAGACT
ATTCAGATAGTAAAGACATTTTAGAAAAAGAGAGCTCAAAAGACTTATACAAGCATTCTACTGATTGTTTAGACTTTGCC
AAAAAGCTTTCTGTTATTGATATGGATGCTCTTTCTAGCAATAAAAAAGATTTCAACTTGGCAGTGTTATACCTATTCTA
CAAAGTCATGAATAGAGCTAAATTAGAAAACAAGCCTTTTTATATATTCATTGATGAAGCTCTGTTATTGAAAATCCTAT
CATGTTAG

Domains

Predicted by InterProScan.

• Helicase HerA, central domain (DUF87) (77-119)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	37.979	97.288	0.369