Detailed information NTG0074450

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: FYK59_RS08715
• Genome accession: NZ_AP019853
• Coordinates: 1685113..1685973 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain SS3160
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1680113..1690973

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FYK59_RS08695 (NGSS3160_17010)	dapD	1680623..1681444 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
FYK59_RS08705 (NGSS3160_17020)	pgi	1681654..1683297 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
FYK59_RS08710 (NGSS3160_17030)	pilG	1683807..1685039 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
FYK59_RS08715 (NGSS3160_17040)	pilD	1685113..1685973 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
FYK59_RS08720 (NGSS3160_17050)	coaE	1685970..1686602 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
FYK59_RS08725 (NGSS3160_17060)	-	1686595..1686804 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
FYK59_RS08730 (NGSS3160_17070)	pilF	1686890..1688566 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
FYK59_RS08740 (NGSS3160_17090)	-	1688904..1689350 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
FYK59_RS08745 (NGSS3160_17100)	-	1689354..1690328 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
FYK59_RS08755 (NGSS3160_17110)	rplU	1690552..1690860 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=74450 FYK59_RS08715 WP_003689814.1 1685113..1685973(+) (pilD) [Neisseria gonorrhoeae strain SS3160]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=74450 FYK59_RS08715 WP_003689814.1 1685113..1685973(+) (pilD) [Neisseria gonorrhoeae strain SS3160]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441