Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   QAP00_RS03025 Genome accession   NZ_CP122949
Coordinates   626301..628670 (-) Length   789 a.a.
NCBI ID   WP_309256884.1    Uniprot ID   -
Organism   Helicobacter pylori strain BS22     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 621301..633670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAP00_RS03010 (QAP00_03015) - 621439..622980 (-) 1542 WP_309256882.1 TrbG/VirB9 family P-type conjugative transfer protein -
  QAP00_RS03015 (QAP00_03020) - 622980..624149 (-) 1170 WP_309256883.1 VirB8/TrbF family protein -
  QAP00_RS03020 (QAP00_03025) - 624266..626298 (-) 2033 Protein_577 type IA DNA topoisomerase -
  QAP00_RS03025 (QAP00_03030) comB4 626301..628670 (-) 2370 WP_309256884.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  QAP00_RS03030 (QAP00_03035) comB3 628717..628974 (-) 258 WP_309256885.1 virB3 type IV secretion protein Machinery gene
  QAP00_RS03035 (QAP00_03040) - 628975..629277 (-) 303 WP_031247542.1 hypothetical protein -
  QAP00_RS03040 (QAP00_03045) - 629274..630798 (-) 1525 Protein_581 hypothetical protein -
  QAP00_RS03050 (QAP00_03055) - 630805..631097 (-) 293 Protein_582 hypothetical protein -
  QAP00_RS03055 (QAP00_03060) - 631117..631896 (-) 780 WP_309256887.1 hypothetical protein -
  QAP00_RS03060 (QAP00_03065) - 632115..632840 (-) 726 WP_000646773.1 NYN domain-containing protein -
  QAP00_RS03065 (QAP00_03070) ruvC 632971..633444 (+) 474 WP_309256888.1 crossover junction endodeoxyribonuclease RuvC -

Sequence

Protein


Download         Length: 789 a.a.        Molecular weight: 91262.73 Da        Isoelectric Point: 7.2921

>NTDB_id=744276 QAP00_RS03025 WP_309256884.1 626301..628670(-) (comB4) [Helicobacter pylori strain BS22]
MKEETNIVGIYNEHYLLSEKSNLVGALKLEGISYLSLDDKEIAQKFNECILALNEIVDGVHFKIVAKRRKIFMYHEYTQE
EISNPFALEVINLWEQGVEDVYQNFYYLIFETKNDSIKGYLERFKKKITTNELENIQENNKQDEVKYQENYFIGFDNFNL
LDKSKILDSIINNVKNMLSGLFVEKIDANSLLNFYMEYINGVPSEYTFARGRLHDGMINSDVHFKKDFFTHIHNSKEIFK
RFISIKTYDIDKIVSTALSSVLHLSLEFDVILNIDNIPKAKAEKRIETKRKRANKSIRVEIDELNDMIKTDRVLMQEISL
NILVHAKTKTDLDSACIEITNLLKQKGIVSTQESIGMLPMFFSFFPNRNRLNFRKRLLSSQNIASLIILEKQNCGFSRNS
WGDRHLTIFRNQDKSPYLFNFHAYEAKRKNDMVSGHTIIFGGTGAGKTTLIEFLITNCFKYEDLSILVLDRNNGMRVMTE
FLDGQYNDSNDFYINPFSLKDTSANCTFLVSWLAFMLNIDEDTKDEKEKKTLSALSKTIRVCYNNITKQGGAIFKLRDFK
DTLERDYLDSKDILEKESSKDLYKHSTDCLDFAKKLSVIDMDALSSSKKDFNLAVLYLFYKVMNRAKLENKPFYIFVDEA
KSVIENPIMLAKIKDTLAQARKLNGVLTLAFQDINQLDGVEGAKSIIENAAQVILYPTNNFEKLESYGILLSPIEKSFLN
KTPLNARQVLVKNLLTQSSVFLEINLEKLNSTSKKFLRAYNSSASSVFELETLKKDNPKDYKEIYLTKE

Nucleotide


Download         Length: 2370 bp        

>NTDB_id=744276 QAP00_RS03025 WP_309256884.1 626301..628670(-) (comB4) [Helicobacter pylori strain BS22]
ATGAAAGAAGAAACTAACATTGTAGGCATTTACAATGAGCATTATCTTTTAAGTGAAAAATCAAACCTTGTAGGCGCTCT
TAAGTTAGAGGGAATTTCTTATTTGTCTTTAGATGACAAAGAAATAGCACAAAAATTTAATGAATGCATTTTAGCTCTTA
ATGAGATTGTAGATGGAGTGCATTTTAAAATCGTAGCTAAAAGGCGTAAGATTTTCATGTACCATGAATATACTCAAGAA
GAGATAAGCAATCCTTTTGCATTAGAGGTTATCAATTTATGGGAGCAAGGGGTTGAGGATGTTTATCAAAATTTCTATTA
CTTAATTTTTGAAACTAAGAATGATAGCATTAAAGGTTATTTGGAACGATTTAAGAAAAAAATCACTACCAATGAATTAG
AAAATATTCAAGAAAATAATAAACAAGATGAAGTTAAATATCAAGAAAACTATTTCATAGGCTTTGATAATTTTAATCTA
TTAGATAAATCTAAAATATTAGACAGCATTATCAATAATGTTAAAAACATGCTTTCTGGCTTGTTTGTAGAAAAAATAGA
CGCCAATAGTTTGCTTAATTTTTACATGGAATATATCAATGGCGTTCCTAGTGAATACACTTTTGCTAGAGGTCGTTTGC
ATGATGGCATGATCAATTCTGATGTCCATTTTAAAAAAGATTTTTTCACTCACATTCATAATAGTAAAGAGATTTTCAAG
CGTTTCATCAGCATTAAGACTTATGATATAGACAAAATTGTCAGCACTGCTCTTTCTTCAGTGTTGCATTTATCTTTAGA
ATTTGATGTGATTTTAAACATTGACAATATTCCTAAAGCAAAGGCTGAAAAAAGGATTGAAACTAAAAGAAAAAGAGCGA
ATAAGAGCATTAGAGTTGAAATTGATGAATTGAATGACATGATTAAAACAGATAGAGTTTTGATGCAGGAGATTTCTTTA
AACATTTTAGTTCATGCCAAAACTAAAACCGATTTAGATAGTGCTTGTATAGAAATCACCAACTTGCTTAAACAAAAAGG
TATTGTAAGCACACAAGAGAGTATTGGCATGTTGCCTATGTTTTTTAGCTTTTTCCCCAATCGTAATCGCTTGAATTTTA
GAAAGCGTTTGTTGTCTAGTCAAAATATTGCTTCTTTAATCATATTGGAAAAACAAAATTGTGGTTTTTCTAGAAATTCA
TGGGGTGATCGCCATTTAACTATTTTTAGAAACCAAGACAAATCGCCTTATTTATTCAATTTCCATGCTTATGAGGCAAA
AAGAAAAAATGATATGGTATCAGGGCATACCATCATCTTTGGTGGCACAGGGGCTGGTAAAACCACTTTAATTGAATTTT
TAATCACCAATTGTTTTAAGTATGAAGATTTAAGTATTTTGGTTTTAGACAGAAATAATGGCATGCGTGTGATGACTGAG
TTTTTAGATGGTCAATACAACGATAGCAATGATTTTTACATTAATCCGTTTTCTTTAAAAGATACAAGCGCTAATTGCAC
CTTCTTAGTGAGTTGGTTGGCATTCATGCTCAATATTGATGAAGATACTAAAGATGAAAAAGAAAAAAAGACTTTAAGCG
CTTTATCCAAAACGATCAGAGTTTGCTATAACAATATCACAAAACAAGGGGGTGCTATTTTTAAATTAAGAGATTTTAAA
GACACGCTAGAAAGAGACTATTTAGATAGCAAAGACATTTTAGAAAAAGAAAGCTCAAAAGACTTATACAAGCATTCTAC
TGATTGTTTAGACTTTGCCAAAAAGCTTTCTGTTATTGATATGGACGCTCTTTCTAGTAGTAAAAAAGATTTCAACTTGG
CAGTGCTATACCTATTCTACAAAGTCATGAATAGAGCTAAATTAGAAAACAAGCCTTTTTATATCTTCGTTGATGAAGCA
AAATCTGTTATTGAAAATCCCATCATGTTAGCTAAAATCAAAGACACGCTCGCTCAAGCTAGAAAACTCAATGGGGTTTT
AACTTTAGCCTTTCAAGACATTAACCAACTTGATGGCGTAGAGGGAGCAAAGTCCATTATAGAAAACGCCGCTCAAGTCA
TACTCTATCCTACAAACAATTTTGAGAAATTAGAGAGCTATGGCATTTTATTAAGTCCTATTGAAAAATCCTTTTTAAAT
AAAACGCCGTTAAACGCTAGGCAAGTATTAGTGAAAAACCTTCTCACTCAATCTAGCGTATTTTTAGAAATCAATTTAGA
AAAACTAAACAGCACTAGTAAAAAATTTTTAAGAGCGTATAACTCTAGTGCGTCTAGCGTTTTTGAATTAGAAACGCTTA
AAAAGGATAATCCAAAAGATTATAAAGAAATTTACTTGACAAAGGAGTAG

Domains

Predicted by InterProScan.

TraM recognition site of TraD and TraG (TraG-D_C)

(632-706)

Helicase HerA, central domain (DUF87)

(430-472)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-374)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

35.804

100

0.361