Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   HZ311_RS09250 Genome accession   NZ_AP019810
Coordinates   1909837..1911141 (-) Length   434 a.a.
NCBI ID   WP_010736524.1    Uniprot ID   A0A1V2ULD8
Organism   Enterococcus mundtii strain 15-1A     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1904837..1916141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HZ311_RS09215 (EM151A_1901) - 1905266..1906222 (-) 957 WP_023518980.1 glycosyltransferase family 2 protein -
  HZ311_RS09220 (EM151A_1902) - 1906360..1906710 (-) 351 WP_019724280.1 PepSY domain-containing protein -
  HZ311_RS09225 (EM151A_1903) pepA 1906912..1907991 (+) 1080 WP_023518981.1 glutamyl aminopeptidase -
  HZ311_RS09230 (EM151A_1904) - 1908115..1908435 (+) 321 WP_023518982.1 thioredoxin family protein -
  HZ311_RS09235 (EM151A_1905) - 1908457..1908912 (+) 456 WP_010736527.1 universal stress protein -
  HZ311_RS09240 (EM151A_1906) - 1908964..1909185 (+) 222 WP_010736526.1 hypothetical protein -
  HZ311_RS09245 (EM151A_1907) ytpR 1909182..1909787 (+) 606 WP_010736525.1 YtpR family tRNA-binding protein -
  HZ311_RS09250 (EM151A_1908) htrA 1909837..1911141 (-) 1305 WP_010736524.1 S1C family serine protease Regulator
  HZ311_RS09255 (EM151A_1909) rlmH 1911570..1912049 (+) 480 WP_010736523.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  HZ311_RS09260 (EM151A_1910) - 1912405..1912800 (+) 396 WP_023518983.1 hypothetical protein -
  HZ311_RS09265 (EM151A_1911) - 1912772..1914037 (+) 1266 WP_051377613.1 hypothetical protein -
  HZ311_RS09270 (EM151A_1912) - 1914034..1914627 (+) 594 WP_023518985.1 hypothetical protein -
  HZ311_RS09275 (EM151A_1913) - 1914632..1914955 (+) 324 WP_269147329.1 DUF4176 domain-containing protein -
  HZ311_RS09280 (EM151A_1914) - 1915156..1915749 (+) 594 WP_023518987.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 45080.01 Da        Isoelectric Point: 4.4838

>NTDB_id=74250 HZ311_RS09250 WP_010736524.1 1909837..1911141(-) (htrA) [Enterococcus mundtii strain 15-1A]
MDRRDVTPKMKKRKSNGIWRKLGLGVVGGVIGGLLTFGIFYAATGGGNSVTTSSSSGTQNASGETVVENVKVNVDSDITS
AVDKVQGAVVSVINLQKQSSSSDPFGSLFGQQQESSGEDGELQAYSEGSGVIYKKEGGSAYIVTNNHVVDGQQGLEVLLK
DGTKVKAELVGTDAYTDLAVLKISADKVDTVASFGDSASLKVGEPAIAIGSPLGSQYANSVTSGIISSLNRQVTSTNESN
ETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSDSSSVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALG
ITMTDLSAVSTQQQEQILKLPSSVTNGVIIRSVQPATPAEKAGLEQYDVITKIDDTEVSSGVELQSVLYGKKVGDTVKIT
YYRGEEEKTVDIKLTIDNTALNQGNSNSSNGSNN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=74250 HZ311_RS09250 WP_010736524.1 1909837..1911141(-) (htrA) [Enterococcus mundtii strain 15-1A]
ATGGACAGAAGAGATGTGACACCAAAAATGAAAAAAAGAAAATCTAATGGCATTTGGCGAAAGCTAGGTCTTGGCGTAGT
TGGTGGCGTGATTGGCGGATTACTGACTTTCGGTATTTTTTATGCAGCAACTGGAGGTGGTAACTCAGTAACGACTTCTT
CTAGCAGTGGGACACAAAATGCATCAGGCGAAACAGTTGTCGAGAATGTAAAAGTCAATGTAGATTCAGATATCACTTCT
GCAGTAGATAAAGTACAAGGAGCAGTTGTTTCTGTTATCAACCTACAAAAACAAAGTTCATCATCTGACCCGTTTGGTTC
ATTATTTGGCCAACAACAAGAAAGTAGTGGCGAAGATGGCGAATTGCAAGCTTACAGTGAAGGTAGCGGTGTGATCTATA
AAAAAGAGGGCGGTTCCGCTTATATCGTGACGAATAATCACGTGGTCGATGGACAACAAGGGTTAGAAGTTTTATTAAAA
GATGGAACAAAAGTGAAAGCAGAATTAGTCGGTACAGATGCTTACACTGATTTAGCTGTGTTGAAAATCAGTGCTGACAA
AGTCGACACTGTTGCTTCATTTGGCGATTCTGCTTCATTGAAAGTCGGCGAACCTGCGATTGCGATTGGTTCTCCTCTAG
GTTCTCAATACGCGAATTCCGTAACATCAGGGATCATTTCTTCCTTGAATCGCCAAGTGACAAGTACCAATGAATCTAAT
GAAACGGTCAATATCAACGCGATTCAAACAGATGCAGCGATCAACCCGGGGAACTCTGGTGGTCCACTAGTTAATATCGA
AGGACAAGTCATTGGTATCAATTCAAGTAAAATTGCATCGACTTCTGATTCTTCAAGTGTAAGTGTTGAAGGAATGGGCT
TTGCGATTCCAAGTAATGATGTCGTAAATATCATCAATCAACTTGAAAAAGATGGAAAAGTAACACGCCCTGCACTGGGT
ATCACAATGACCGATCTTTCCGCCGTTTCTACACAACAACAGGAACAGATCTTGAAATTACCATCTTCTGTAACAAATGG
CGTGATCATTCGTTCGGTTCAACCAGCAACGCCTGCGGAAAAAGCTGGCTTAGAACAATATGATGTCATCACAAAAATCG
ATGATACAGAAGTCTCATCTGGTGTTGAATTACAGTCTGTGCTTTATGGTAAAAAAGTTGGTGACACTGTGAAGATCACT
TATTACCGTGGCGAAGAAGAAAAAACTGTAGATATCAAATTGACAATTGATAATACTGCATTAAATCAAGGAAATTCAAA
TAGTTCCAATGGCTCAAATAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(13-416)

Trypsin-like peptidase domain (Trypsin_2)

(128-273)

PDZ domain (PDZ_2)

(317-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V2ULD8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.01

90.092

0.505
  htrA Streptococcus gordonii str. Challis substr. CH1

51.852

93.318

0.484
  htrA Streptococcus mitis NCTC 12261

52.778

91.244

0.482
  htrA Streptococcus pneumoniae Rx1

58.631

77.419

0.454
  htrA Streptococcus pneumoniae D39

58.631

77.419

0.454
  htrA Streptococcus pneumoniae R6

58.631

77.419

0.454
  htrA Streptococcus pneumoniae TIGR4

58.631

77.419

0.454

Multiple sequence alignment