Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BsBEST3145_RS02890 Genome accession   NZ_AP024625
Coordinates   554801..555442 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain BEST3109     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 549801..560442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BsBEST3145_RS02860 (BsBEST3109_05170) ydfE 550996..551619 (-) 624 WP_003243530.1 flavin reductase family protein -
  BsBEST3145_RS02865 (BsBEST3109_05180) ydfF 551709..552389 (+) 681 WP_003244115.1 helix-turn-helix transcriptional regulator -
  BsBEST3145_RS02870 (BsBEST3109_05190) ydfG 552469..552912 (-) 444 WP_003242768.1 carboxymuconolactone decarboxylase family protein -
  BsBEST3145_RS02875 (BsBEST3109_05200) - 552998..553177 (-) 180 WP_010886421.1 hypothetical protein -
  BsBEST3145_RS02880 - 553174..553317 (-) 144 WP_003243880.1 hypothetical protein -
  BsBEST3145_RS02885 (BsBEST3109_05210) ydfH 553585..554808 (+) 1224 WP_010886422.1 two-component system sensor histidine kinase YdfH -
  BsBEST3145_RS02890 (BsBEST3109_05220) vraR 554801..555442 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  BsBEST3145_RS02895 (BsBEST3109_05230) pleJ 555558..557732 (+) 2175 WP_003243548.1 MMPL family transporter -
  BsBEST3145_RS02900 (BsBEST3109_05240) cesA 558144..559046 (-) 903 WP_003242638.1 carboxylesterase -
  BsBEST3145_RS02905 (BsBEST3109_05250) ydfK 559248..559937 (-) 690 WP_003242513.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=74131 BsBEST3145_RS02890 WP_003244318.1 554801..555442(+) (vraR) [Bacillus subtilis strain BEST3109]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=74131 BsBEST3145_RS02890 WP_003244318.1 554801..555442(+) (vraR) [Bacillus subtilis strain BEST3109]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTAGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362

Multiple sequence alignment