Detailed information NTG0740344

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: QAO16_RS11915
• Genome accession: NZ_CP122489
• Coordinates: 2391343..2393448 (-)
• Length: 701 a.a.
• NCBI ID: WP_411896580.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain GE-MSSA42
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2386343..2398448

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO16_RS11900 (QAO16_11885)	-	2388857..2389084 (+)	228	WP_000932073.1	FeoA family protein	-
QAO16_RS11905 (QAO16_11890)	feoB	2389096..2391090 (+)	1995	WP_000432892.1	ferrous iron transport protein B	-
QAO16_RS11910 (QAO16_11895)	-	2391103..2391273 (+)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
QAO16_RS11915 (QAO16_11900)	clpE	2391343..2393448 (-)	2106	WP_411896580.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
QAO16_RS11920 (QAO16_11905)	-	2393811..2394332 (+)	522	WP_123875515.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
QAO16_RS11925 (QAO16_11910)	-	2394503..2395669 (-)	1167	WP_000172190.1	hydroxymethylglutaryl-CoA synthase	-
QAO16_RS11930 (QAO16_11915)	-	2395924..2397204 (+)	1281	WP_001191011.1	hydroxymethylglutaryl-CoA reductase, degradative	-
QAO16_RS11935 (QAO16_11920)	-	2397344..2397775 (-)	432	WP_000875613.1	CHAP domain-containing protein	-
QAO16_RS11940 (QAO16_11925)	-	2398163..2398381 (-)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 78010.65 Da
• Isoelectric Point: 4.7794

>NTDB_id=740344 QAO16_RS11915 WP_411896580.1 2391343..2393448(-) (clpE) [Staphylococcus aureus strain GE-MSSA42]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVTTEKRISELEHDKRKAVSAEEYKKADDIQKEIKSLQDKLENSNGEHTAVAKVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=740344 QAO16_RS11915 WP_411896580.1 2391343..2393448(-) (clpE) [Staphylococcus aureus strain GE-MSSA42]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
GTCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCCTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGTCCTGCTATTGATAAAGTCACGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAAAGAAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAAAGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGTAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTGGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACACTGAAGAAAAAGATATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTGTTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCACAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.452	92.154	0.447
clpE	Streptococcus pneumoniae Rx1	47.812	88.017	0.421
clpE	Streptococcus pneumoniae D39	47.812	88.017	0.421
clpE	Streptococcus pneumoniae R6	47.812	88.017	0.421
clpE	Streptococcus pneumoniae TIGR4	47.812	88.017	0.421
clpC	Lactococcus lactis subsp. cremoris KW2	46.497	89.586	0.417
clpC	Bacillus subtilis subsp. subtilis str. 168	43.969	93.438	0.411
clpC	Streptococcus thermophilus LMD-9	44.96	89.158	0.401
clpC	Streptococcus thermophilus LMG 18311	44.64	89.158	0.398
clpC	Streptococcus pneumoniae TIGR4	43.68	89.158	0.389
clpC	Streptococcus pneumoniae Rx1	43.68	89.158	0.389
clpC	Streptococcus pneumoniae D39	43.68	89.158	0.389
clpC	Streptococcus mutans UA159	44.065	87.732	0.387
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.326	88.302	0.374