Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QBL25_RS22215 Genome accession   NZ_CP122310
Coordinates   5066339..5067010 (+) Length   223 a.a.
NCBI ID   WP_409058771.1    Uniprot ID   -
Organism   Streptomyces sp. SYP-A7185     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5061339..5072010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QBL25_RS22195 - 5061868..5062341 (+) 474 WP_409058768.1 carboxymuconolactone decarboxylase family protein -
  QBL25_RS22200 - 5062390..5063067 (+) 678 WP_409058769.1 TetR/AcrR family transcriptional regulator -
  QBL25_RS22205 - 5063131..5063607 (-) 477 WP_409062737.1 DUF5707 domain-containing protein -
  QBL25_RS22210 - 5063943..5066342 (+) 2400 WP_409058770.1 histidine kinase -
  QBL25_RS22215 vraR 5066339..5067010 (+) 672 WP_409058771.1 response regulator Regulator
  QBL25_RS22220 - 5067044..5067328 (+) 285 WP_409058772.1 SCO4225 family membrane protein -
  QBL25_RS22225 - 5067405..5068145 (-) 741 WP_409058773.1 helix-turn-helix domain-containing protein -
  QBL25_RS22230 - 5068424..5069095 (+) 672 WP_409058774.1 DUF4097 family beta strand repeat-containing protein -
  QBL25_RS22235 - 5069482..5070195 (+) 714 WP_409058775.1 GIY-YIG nuclease family protein -
  QBL25_RS22240 - 5070399..5070716 (-) 318 WP_409062974.1 hypothetical protein -
  QBL25_RS22245 - 5070732..5071055 (-) 324 Protein_4387 HNH endonuclease -
  QBL25_RS22250 - 5071284..5071736 (+) 453 Protein_4388 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23406.88 Da        Isoelectric Point: 5.0554

>NTDB_id=738882 QBL25_RS22215 WP_409058771.1 5066339..5067010(+) (vraR) [Streptomyces sp. SYP-A7185]
MSLKVLVVDDQGIVRAGFAAVIDAEDDMTVVGEAADGVDAVRLAAELAPDVVVMDVRMPELDGIAATRIITGKENAPRVL
VLTTFDLDAYVFDALRAGASGFLLKDVHASELLQGIRVVAAGESVLAPSATRRLIGHYASGARPGASEQDLATLTGSQRN
VLTLLASGLNNAEIAQELRITVGTVKSHVNALLRKLGLRDRVQATILAYDLGLARPNPPGTHL

Nucleotide


Download         Length: 672 bp        

>NTDB_id=738882 QBL25_RS22215 WP_409058771.1 5066339..5067010(+) (vraR) [Streptomyces sp. SYP-A7185]
ATGAGCCTGAAGGTGCTGGTCGTCGACGACCAGGGGATCGTACGGGCGGGGTTCGCCGCGGTGATCGACGCCGAGGACGA
CATGACGGTCGTCGGCGAGGCCGCCGACGGCGTCGACGCGGTGCGCCTCGCGGCCGAGCTGGCGCCCGACGTGGTCGTCA
TGGACGTACGGATGCCCGAACTGGACGGGATCGCCGCCACCCGGATCATCACGGGCAAGGAGAACGCGCCCCGGGTCCTG
GTCCTGACCACGTTCGACCTCGACGCGTACGTCTTCGACGCCCTGCGCGCGGGAGCCTCGGGCTTCCTGCTCAAGGACGT
GCACGCGTCCGAACTGCTGCAAGGCATCCGGGTGGTGGCGGCGGGCGAGAGCGTGCTCGCCCCGTCGGCGACCCGCCGAC
TGATCGGCCACTACGCGTCCGGGGCCCGCCCCGGAGCGAGTGAGCAGGACCTCGCCACCCTGACCGGCAGCCAGCGCAAC
GTCCTGACGCTGCTCGCGTCGGGCCTGAACAACGCGGAGATCGCGCAGGAGCTGCGGATCACCGTCGGCACGGTGAAGTC
CCACGTGAACGCCCTGCTGCGCAAGCTCGGCCTGCGCGACCGCGTCCAGGCCACGATCCTCGCCTACGACCTGGGCCTGG
CCCGCCCGAATCCGCCGGGCACCCATCTCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.674

96.413

0.363