Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | OE961_RS02680 | Genome accession | NZ_CP107223 |
| Coordinates | 517388..518053 (+) | Length | 221 a.a. |
| NCBI ID | WP_003690897.1 | Uniprot ID | A0AB74EDV3 |
| Organism | Neisseria gonorrhoeae strain H035 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 505741..558585 | 517388..518053 | within | 0 |
Gene organization within MGE regions
Location: 505741..558585
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OE961_RS02625 (OE961_02625) | - | 505741..506724 (+) | 984 | WP_003687900.1 | ribose-phosphate pyrophosphokinase | - |
| OE961_RS02630 (OE961_02630) | - | 506791..507363 (+) | 573 | WP_003687901.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| OE961_RS02635 (OE961_02635) | - | 507489..508658 (-) | 1170 | WP_003690889.1 | D-alanyl-D-alanine carboxypeptidase family protein | - |
| OE961_RS02640 (OE961_02640) | ilvA | 508807..510333 (+) | 1527 | WP_003690890.1 | threonine ammonia-lyase, biosynthetic | - |
| OE961_RS02645 (OE961_02645) | - | 510389..511465 (-) | 1077 | WP_003687905.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| OE961_RS02650 (OE961_02650) | cysW | 511462..512322 (-) | 861 | WP_003690891.1 | sulfate ABC transporter permease subunit CysW | - |
| OE961_RS02655 (OE961_02655) | cysT | 512511..513340 (-) | 830 | Protein_515 | sulfate ABC transporter permease subunit CysT | - |
| OE961_RS02660 (OE961_02660) | - | 513526..513858 (+) | 333 | WP_003687908.1 | hypothetical protein | - |
| OE961_RS02665 (OE961_02665) | - | 514188..514697 (+) | 510 | WP_003687909.1 | isoprenylcysteine carboxyl methyltransferase family protein | - |
| OE961_RS02670 (OE961_02670) | - | 514929..515510 (-) | 582 | WP_003690895.1 | superoxide dismutase | - |
| OE961_RS02675 (OE961_02675) | dnaB | 515674..517080 (+) | 1407 | WP_003690896.1 | replicative DNA helicase | - |
| OE961_RS02680 (OE961_02680) | pilH | 517388..518053 (+) | 666 | WP_003690897.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| OE961_RS02685 (OE961_02685) | pilI | 518085..518693 (+) | 609 | WP_003690898.1 | type IV pilus modification protein PilV | Machinery gene |
| OE961_RS02690 (OE961_02690) | pilJ | 518690..519631 (+) | 942 | WP_003690899.1 | PilW family protein | Machinery gene |
| OE961_RS02695 (OE961_02695) | pilK | 519610..520218 (+) | 609 | WP_003690900.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| OE961_RS02700 (OE961_02700) | pilL | 520220..520693 (+) | 474 | WP_025455782.1 | PilX family type IV pilin | Machinery gene |
| OE961_RS02705 (OE961_02705) | - | 521305..521750 (-) | 446 | Protein_525 | AzlC family ABC transporter permease | - |
| OE961_RS02710 (OE961_02710) | dut | 521916..522368 (+) | 453 | WP_003690909.1 | dUTP diphosphatase | - |
| OE961_RS02715 (OE961_02715) | dapC | 522446..523633 (+) | 1188 | WP_003690911.1 | succinyldiaminopimelate transaminase | - |
| OE961_RS02720 (OE961_02720) | yaaA | 523789..524568 (+) | 780 | WP_003690913.1 | peroxide stress protein YaaA | - |
| OE961_RS02735 (OE961_02735) | - | 525099..526295 (+) | 1197 | WP_003704323.1 | integrase arm-type DNA-binding domain-containing protein | - |
| OE961_RS02740 (OE961_02740) | - | 526651..526920 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| OE961_RS02745 (OE961_02745) | - | 527115..527798 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| OE961_RS11505 | - | 528079..528345 (-) | 267 | Protein_532 | hypothetical protein | - |
| OE961_RS02755 (OE961_02755) | - | 528456..528671 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| OE961_RS02760 (OE961_02760) | - | 528723..529214 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| OE961_RS02765 (OE961_02765) | - | 529211..529393 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| OE961_RS02770 (OE961_02770) | - | 529533..530219 (-) | 687 | WP_003691532.1 | phage replication initiation protein, NGO0469 family | - |
| OE961_RS02775 (OE961_02775) | - | 530288..530449 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| OE961_RS02780 (OE961_02780) | - | 530446..530724 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| OE961_RS02785 (OE961_02785) | - | 530877..531209 (-) | 333 | WP_003691528.1 | hypothetical protein | - |
| OE961_RS02790 (OE961_02790) | - | 531350..531625 (-) | 276 | WP_003691527.1 | hypothetical protein | - |
| OE961_RS02795 (OE961_02795) | - | 531622..532098 (-) | 477 | WP_002255718.1 | DUF6948 domain-containing protein | - |
| OE961_RS02800 (OE961_02800) | - | 532131..532331 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| OE961_RS02805 (OE961_02805) | - | 532529..532942 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| OE961_RS02810 (OE961_02810) | - | 532939..533400 (-) | 462 | WP_003687965.1 | helix-turn-helix domain-containing protein | - |
| OE961_RS02815 (OE961_02815) | - | 533417..533854 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| OE961_RS02820 (OE961_02820) | - | 533969..534685 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| OE961_RS02825 (OE961_02825) | - | 534760..534990 (+) | 231 | WP_020997318.1 | Cro/CI family transcriptional regulator | - |
| OE961_RS02830 (OE961_02830) | - | 535070..535225 (+) | 156 | WP_047923772.1 | hypothetical protein | - |
| OE961_RS02835 (OE961_02835) | - | 535202..535390 (-) | 189 | WP_047926457.1 | hypothetical protein | - |
| OE961_RS02840 (OE961_02840) | - | 535564..535791 (+) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| OE961_RS02845 (OE961_02845) | - | 535788..536798 (+) | 1011 | WP_014580341.1 | helix-turn-helix domain-containing protein | - |
| OE961_RS02850 (OE961_02850) | - | 536810..537589 (+) | 780 | WP_025455804.1 | ATP-binding protein | - |
| OE961_RS02855 (OE961_02855) | - | 537582..537830 (+) | 249 | WP_106158912.1 | hypothetical protein | - |
| OE961_RS02860 (OE961_02860) | - | 537906..538400 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| OE961_RS02865 (OE961_02865) | - | 538577..538726 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| OE961_RS02870 (OE961_02870) | - | 538755..539036 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| OE961_RS02875 (OE961_02875) | - | 539027..539464 (+) | 438 | WP_229701788.1 | RusA family crossover junction endodeoxyribonuclease | - |
| OE961_RS02880 (OE961_02880) | - | 539457..539762 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| OE961_RS02885 (OE961_02885) | - | 539759..540142 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| OE961_RS02890 (OE961_02890) | - | 540133..540651 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| OE961_RS02895 (OE961_02895) | - | 540716..541138 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| OE961_RS02900 (OE961_02900) | - | 541138..541677 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| OE961_RS02905 (OE961_02905) | - | 541658..542932 (+) | 1275 | WP_014580143.1 | PBSX family phage terminase large subunit | - |
| OE961_RS02910 (OE961_02910) | - | 542917..545184 (+) | 2268 | WP_225577699.1 | hypothetical protein | - |
| OE961_RS02915 (OE961_02915) | - | 545421..546617 (+) | 1197 | WP_003690925.1 | hypothetical protein | - |
| OE961_RS02920 (OE961_02920) | - | 546614..547828 (+) | 1215 | WP_047954539.1 | hypothetical protein | - |
| OE961_RS11640 | - | 548031..553940 (+) | 5910 | WP_033909227.1 | PLxRFG domain-containing protein | - |
| OE961_RS02935 (OE961_02935) | - | 554566..555861 (+) | 1296 | WP_003690933.1 | DUF4043 family protein | - |
| OE961_RS02940 (OE961_02940) | - | 555916..556389 (+) | 474 | WP_003690936.1 | hypothetical protein | - |
| OE961_RS02945 (OE961_02945) | - | 556395..556880 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| OE961_RS02950 (OE961_02950) | - | 556877..557551 (+) | 675 | WP_003687998.1 | hypothetical protein | - |
| OE961_RS02955 (OE961_02955) | - | 557554..557703 (+) | 150 | WP_003706419.1 | hypothetical protein | - |
| OE961_RS02960 (OE961_02960) | - | 557740..558585 (-) | 846 | WP_003690940.1 | BRO family protein | - |
Sequence
Protein
Download Length: 221 a.a. Molecular weight: 24613.05 Da Isoelectric Point: 9.4066
>NTDB_id=738639 OE961_RS02680 WP_003690897.1 517388..518053(+) (pilH) [Neisseria gonorrhoeae strain H035]
MCTRKQQGFTLIELLIVIAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDLGKKEQGMLAFGDKNDNKAYDGDSADVFLRNVVLNDDIKDKRINYTFNHIAFGQTRSTADRVVWTFNQNGTFGYSS
DRNLKNNSKFVYSDGYIQIVLTDAKAVSAGEKKFRSAVVLIDSSGRVEVCPRNDRRAVCQH
MCTRKQQGFTLIELLIVIAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDLGKKEQGMLAFGDKNDNKAYDGDSADVFLRNVVLNDDIKDKRINYTFNHIAFGQTRSTADRVVWTFNQNGTFGYSS
DRNLKNNSKFVYSDGYIQIVLTDAKAVSAGEKKFRSAVVLIDSSGRVEVCPRNDRRAVCQH
Nucleotide
Download Length: 666 bp
>NTDB_id=738639 OE961_RS02680 WP_003690897.1 517388..518053(+) (pilH) [Neisseria gonorrhoeae strain H035]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAATAGAGCTGCTCATCGTGATAGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTGGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGTGA
TTCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTCAAACACGGTCGACTGCCGATCGTGTTGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTCGTCC
GATCGGAATCTCAAGAATAATTCCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGTTGACAGATGCGAAGGCGGT
TTCTGCCGGTGAAAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGCCCTAGAAACG
ATAGGCGTGCCGTATGCCAACATTAA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAATAGAGCTGCTCATCGTGATAGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTGGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGTGA
TTCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTCAAACACGGTCGACTGCCGATCGTGTTGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTCGTCC
GATCGGAATCTCAAGAATAATTCCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGTTGACAGATGCGAAGGCGGT
TTCTGCCGGTGAAAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGCCCTAGAAACG
ATAGGCGTGCCGTATGCCAACATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
82.805 |
100 |
0.828 |