Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   QBE57_RS08450 Genome accession   NZ_CP121670
Coordinates   1719992..1721929 (-) Length   645 a.a.
NCBI ID   WP_012774891.1    Uniprot ID   -
Organism   Streptococcus suis strain HBXY-SL     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1714992..1726929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QBE57_RS08425 spx 1715014..1715412 (-) 399 WP_002939362.1 transcriptional regulator Spx -
  QBE57_RS08430 recA 1715648..1716799 (-) 1152 WP_011922545.1 recombinase RecA Machinery gene
  QBE57_RS08435 cinA 1716851..1718032 (-) 1182 WP_012774894.1 competence/damage-inducible protein A Machinery gene
  QBE57_RS08440 - 1718069..1718638 (-) 570 WP_012774893.1 DNA-3-methyladenine glycosylase I -
  QBE57_RS08445 ruvA 1719363..1719953 (-) 591 WP_011921679.1 Holliday junction branch migration protein RuvA Machinery gene
  QBE57_RS08450 hexB 1719992..1721929 (-) 1938 WP_012774891.1 DNA mismatch repair endonuclease MutL Machinery gene
  QBE57_RS08455 - 1722047..1723570 (-) 1524 WP_011921677.1 Heme/copper-type cytochrome/quinol oxidase subunit 1 -
  QBE57_RS08460 - 1723761..1724981 (-) 1221 WP_012774890.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  QBE57_RS08465 - 1725121..1726059 (+) 939 WP_011921674.1 IS4 family transposase -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72995.17 Da        Isoelectric Point: 5.1152

>NTDB_id=738607 QBE57_RS08450 WP_012774891.1 1719992..1721929(-) (hexB) [Streptococcus suis strain HBXY-SL]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFVLVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENR
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGSNQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=738607 QBE57_RS08450 WP_012774891.1 1719992..1721929(-) (hexB) [Streptococcus suis strain HBXY-SL]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCCCTGCCCTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAT
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCCTT
TGTCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTTATCAACGGTCGCTATATCAAGAATTTTTTGCTTAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGCTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCACTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAGA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCACAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAAGTTGACAATTCAGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTGGAAGAATATGGATCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCCATCATGATGTCTTGTAAACGGTCAATCAAGGCCAATCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAATTGCCCGCACGGCC
GCCCAGTCTTAGTGCATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGT
GAATTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(447-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.462

100

0.73