Detailed information NTG0073835

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FPG46_RS14415
• Genome accession: NZ_AP019751
• Coordinates: 2799838..2800725 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain JRA307
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2794838..2805725

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPG46_RS14380	-	2794857..2794949 (+)	93	WP_010956583.1	hypothetical protein	-
FPG46_RS14385 (SAJRA307_26360)	-	2795057..2795554 (-)	498	WP_001065268.1	glutathione peroxidase	-
FPG46_RS14390 (SAJRA307_26370)	-	2795564..2795824 (-)	261	WP_001791974.1	hypothetical protein	-
FPG46_RS14400	-	2796206..2796319 (-)	114	Protein_2738	hypothetical protein	-
FPG46_RS14405 (SAJRA307_26380)	-	2796978..2798978 (-)	2001	WP_000776740.1	ABC transporter permease	-
FPG46_RS14410 (SAJRA307_26390)	-	2798975..2799730 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FPG46_RS14415 (SAJRA307_26400)	braS	2799838..2800725 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FPG46_RS14420 (SAJRA307_26410)	braR	2800736..2801401 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FPG46_RS14425 (SAJRA307_26420)	-	2801427..2801627 (-)	201	WP_000604727.1	hypothetical protein	-
FPG46_RS14430 (SAJRA307_26430)	-	2801825..2803249 (+)	1425	WP_000953748.1	alkaline phosphatase	-
FPG46_RS15485 (SAJRA307_26440)	-	2803309..2803410 (-)	102	WP_000731972.1	SE2200 family small protein	-
FPG46_RS14440 (SAJRA307_26450)	-	2803532..2803987 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FPG46_RS14445 (SAJRA307_26460)	-	2804232..2804993 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=73835 FPG46_RS14415 WP_000143417.1 2799838..2800725(-) (braS) [Staphylococcus aureus strain JRA307]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=73835 FPG46_RS14415 WP_000143417.1 2799838..2800725(-) (braS) [Staphylococcus aureus strain JRA307]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99