Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   P8R99_RS09315 Genome accession   NZ_CP121160
Coordinates   1764450..1766282 (+) Length   610 a.a.
NCBI ID   WP_000340813.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain S5     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1759450..1771282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R99_RS09300 - 1760107..1760661 (+) 555 Protein_1752 ImmA/IrrE family metallo-endopeptidase -
  P8R99_RS09305 ltrA 1761214..1762491 (+) 1278 WP_001292556.1 group II intron reverse transcriptase/maturase -
  P8R99_RS09310 - 1762700..1764448 (+) 1749 WP_222351475.1 DNA topoisomerase -
  P8R99_RS09315 clpE 1764450..1766282 (+) 1833 WP_000340813.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  P8R99_RS09320 - 1766374..1766721 (+) 348 WP_000837589.1 TrbC/VirB2 family protein -
  P8R99_RS09325 - 1766732..1767805 (+) 1074 WP_000874142.1 hypothetical protein -
  P8R99_RS09330 - 1767823..1768596 (+) 774 WP_000163066.1 LPXTG cell wall anchor domain-containing protein -
  P8R99_RS09335 - 1768661..1770865 (+) 2205 WP_000191306.1 LPXTG cell wall anchor domain-containing protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68501.21 Da        Isoelectric Point: 4.9713

>NTDB_id=736273 P8R99_RS09315 WP_000340813.1 1764450..1766282(+) (clpE) [Streptococcus agalactiae strain S5]
MDDELKTPYLDKYTDNLSAKVAKKSDDYQVYGRDKEVQAVIISLLRRTKNNPILVGEAGVGKTAIVEGLTLAIMRDQVPE
ALKGLTVRSLELSSLMSEEDGGFIAKFKKIIEEMVATRGHNLLFVDEFHTIVGAGSQDGQALDAGNVIKPVLARGDIQLI
GATTLDEFHDYIETDRALERRMQPVMVEEPTIPQAITIIDQAKGIYEKFHGIQISSEAVRQAVRLSVRYITDRFLPDKAF
DLIDEASTIAAAEGKATVTDEDIAQVLKDKTGIPVTTILKGDQDRLDGFKEKLMDRVKGQEDAIEAIVDAVTIAQAGLQD
ENKPISSFLFLGPTGVGKTELSKAVAEALFDDEDAMIRFDMSEFKKKEDVAKLIGNRETRTKGQLTEGVKRKPYSVLLLD
EVEKAHSEVMDLFLQVLDDGRLTDSSGRLISFKNVIVIMTTNIGAKKIINKWELKGNFKELTDRDRQQFEKSMDSELQNE
FRPEFLNRIENKIIFNLLERNVIEEIAEKNLSKISDRMKRQNLTLSYEPSLIQYLSDVGTDVKNGARPLERLIKRKVLAP
ISSKSLTLDKGKQTYNVHLWVDGEAPDNQHRKDLRQIHLDIEGELDSFFS

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=736273 P8R99_RS09315 WP_000340813.1 1764450..1766282(+) (clpE) [Streptococcus agalactiae strain S5]
GTGGATGATGAATTGAAGACCCCTTATCTTGATAAGTACACTGATAATTTGTCAGCTAAGGTTGCTAAAAAATCAGACGA
CTATCAAGTGTACGGCCGTGATAAGGAAGTACAAGCAGTCATTATCTCTCTTCTCAGACGAACGAAAAATAATCCTATTC
TGGTAGGAGAAGCAGGAGTTGGTAAAACAGCTATTGTAGAGGGGTTAACACTTGCTATTATGCGTGACCAAGTTCCTGAA
GCTTTAAAAGGTTTAACGGTTCGTTCCTTGGAACTATCCAGCTTGATGAGTGAAGAAGATGGTGGCTTCATTGCTAAGTT
CAAGAAGATTATTGAGGAGATGGTTGCCACACGTGGTCATAATCTTCTCTTTGTAGATGAATTTCATACCATAGTTGGTG
CAGGTAGTCAGGACGGACAAGCCCTCGATGCAGGAAATGTGATTAAACCAGTTTTGGCACGTGGGGATATTCAGTTGATT
GGAGCAACTACCTTAGATGAATTCCATGATTATATTGAAACTGATAGAGCCTTAGAGCGTCGGATGCAACCTGTTATGGT
TGAAGAGCCAACGATTCCACAAGCTATAACTATTATTGATCAAGCAAAAGGGATTTATGAAAAGTTTCATGGGATTCAAA
TTTCCTCAGAAGCTGTTCGTCAAGCGGTCCGTCTATCTGTCCGCTATATTACAGATCGTTTTTTACCAGATAAAGCTTTT
GACTTAATCGATGAAGCTTCTACGATTGCTGCCGCTGAAGGAAAAGCAACCGTAACTGATGAAGATATAGCCCAGGTCTT
AAAAGATAAAACAGGAATTCCTGTGACAACAATTCTGAAAGGTGATCAGGATCGCTTAGACGGTTTCAAAGAAAAGCTGA
TGGATCGAGTCAAAGGTCAGGAAGATGCGATAGAGGCCATAGTAGATGCGGTAACTATTGCTCAGGCAGGTTTGCAAGAT
GAAAACAAGCCTATCTCTTCATTTCTCTTTCTTGGGCCGACTGGAGTTGGTAAAACAGAATTATCCAAGGCCGTCGCAGA
AGCACTTTTTGATGATGAAGATGCTATGATTCGCTTTGATATGTCTGAGTTCAAGAAAAAAGAAGATGTGGCCAAGCTGA
TTGGTAATCGTGAGACAAGAACTAAAGGGCAGCTAACTGAAGGAGTTAAACGGAAGCCTTACTCTGTCTTGTTGCTAGAT
GAAGTTGAAAAGGCTCATAGTGAGGTTATGGATCTCTTCTTGCAAGTGTTAGATGATGGTCGCTTAACAGATAGTTCTGG
ACGTTTGATTAGCTTTAAGAACGTTATTGTCATTATGACAACCAACATTGGGGCTAAGAAGATTATCAATAAGTGGGAGC
TGAAGGGGAACTTCAAAGAGTTAACTGATCGTGATAGACAGCAATTTGAAAAGTCTATGGACAGTGAGTTACAAAATGAG
TTTCGTCCAGAGTTTCTTAATCGGATTGAAAATAAGATTATCTTCAACCTTTTAGAGAGAAATGTCATTGAAGAAATTGC
AGAGAAGAACCTTTCTAAAATTTCAGATCGAATGAAGCGACAAAATTTGACGCTATCTTATGAGCCTAGCTTGATTCAGT
ATCTCTCTGATGTGGGTACAGACGTGAAAAATGGTGCACGTCCTTTGGAACGTTTAATTAAACGAAAAGTTTTAGCGCCT
ATTTCGTCCAAGAGTCTAACCTTGGATAAAGGTAAACAAACCTATAATGTACATTTATGGGTTGATGGTGAAGCACCAGA
TAATCAACACAGGAAAGATTTGAGACAAATTCATTTGGATATTGAAGGAGAACTGGATTCCTTTTTCAGCTGA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(53-165)

AAA lid domain (AAA_lid_9)

(192-263)

AAA domain (Cdc48 subfamily) (AAA_2)

(323-490)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(498-567)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

42.881

99.016

0.425
  clpE Streptococcus pneumoniae D39

42.881

99.016

0.425
  clpE Streptococcus pneumoniae R6

42.881

99.016

0.425
  clpE Streptococcus pneumoniae TIGR4

42.881

99.016

0.425
  clpC Bacillus subtilis subsp. subtilis str. 168

41.586

100

0.421
  clpE Streptococcus mutans UA159

42.01

99.508

0.418
  clpC Lactococcus lactis subsp. cremoris KW2

40.362

99.508

0.402
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

39.152

100

0.393
  clpC Streptococcus mutans UA159

39.597

97.705

0.387
  clpC Streptococcus thermophilus LMD-9

39.394

97.377

0.384
  clpC Streptococcus thermophilus LMG 18311

39.226

97.377

0.382
  clpC Streptococcus pneumoniae Rx1

39.358

97.049

0.382
  clpC Streptococcus pneumoniae TIGR4

39.358

97.049

0.382
  clpC Streptococcus pneumoniae D39

39.358

97.049

0.382