Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   DO80_RS03095 Genome accession   NZ_AP019730
Coordinates   593184..594968 (-) Length   594 a.a.
NCBI ID   WP_108303650.1    Uniprot ID   -
Organism   Helicobacter pylori strain TN2wt     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 588184..599968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DO80_RS03065 (DO80_05800) - 588758..589006 (+) 249 WP_000790557.1 RNA-binding protein -
  DO80_RS03070 (DO80_05810) - 589222..590046 (-) 825 WP_108303652.1 glycosyltransferase family 25 protein -
  DO80_RS03075 (DO80_05820) trxB 590213..591148 (-) 936 WP_024773194.1 thioredoxin-disulfide reductase -
  DO80_RS03080 (DO80_05830) trxA 591154..591474 (-) 321 WP_000020200.1 thioredoxin -
  DO80_RS03085 (DO80_05840) - 591563..591907 (-) 345 WP_108303651.1 YraN family protein -
  DO80_RS03090 (DO80_05850) - 591908..593173 (-) 1266 WP_050832912.1 homoserine dehydrogenase -
  DO80_RS03095 (DO80_05860) uvrC 593184..594968 (-) 1785 WP_108303650.1 excinuclease ABC subunit UvrC Machinery gene
  DO80_RS03100 (DO80_05870) - 594969..595430 (-) 462 WP_000437191.1 hypothetical protein -
  DO80_RS03105 - 595422..595601 (+) 180 WP_108303649.1 hypothetical protein -
  DO80_RS03110 (DO80_05880) - 595613..596254 (-) 642 WP_000659355.1 ABC transporter ATP-binding protein -
  DO80_RS03115 (DO80_05890) - 596258..597919 (-) 1662 WP_108303648.1 ABC transporter permease/substrate-binding protein -
  DO80_RS03120 (DO80_05900) - 598098..598535 (-) 438 WP_001031792.1 hypothetical protein -
  DO80_RS03125 (DO80_05910) motB 598539..599306 (-) 768 WP_108303647.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68880.26 Da        Isoelectric Point: 9.8178

>NTDB_id=73627 DO80_RS03095 WP_108303650.1 593184..594968(-) (uvrC) [Helicobacter pylori strain TN2wt]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVHNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKKLELKMKRLSNNLRFEEALIYRDRITKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFKLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=73627 DO80_RS03095 WP_108303650.1 593184..594968(-) (uvrC) [Helicobacter pylori strain TN2wt]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCACAATAATGAAATCACGCCTA
ACCATCGCACCAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAGCTCAAGCCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAAAGCTTGAATTAA
AAATGAAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTACAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTTTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTACTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.128

100

0.961

Multiple sequence alignment