Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   OCL42_RS10250 Genome accession   NZ_CP106807
Coordinates   1945431..1948532 (+) Length   1033 a.a.
NCBI ID   WP_263074895.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 10736     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1940431..1953532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCL42_RS10230 (OCL42_10230) - 1941124..1941573 (-) 450 WP_003688065.1 CopD family copper resistance protein -
  OCL42_RS10235 (OCL42_10235) waaA 1941614..1942885 (-) 1272 WP_025455875.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  OCL42_RS10240 (OCL42_10240) gnd 1942948..1944396 (-) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  OCL42_RS10245 (OCL42_10245) - 1944476..1944739 (-) 264 WP_017147189.1 hypothetical protein -
  OCL42_RS10250 (OCL42_10250) pilC 1945431..1948532 (+) 3102 WP_263074895.1 PilC family type IV pilus tip adhesin Machinery gene
  OCL42_RS10255 (OCL42_10255) - 1949266..1949550 (+) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  OCL42_RS10260 (OCL42_10260) yccS 1950225..1952159 (-) 1935 WP_263074896.1 YccS family putative transporter -
  OCL42_RS10265 (OCL42_10265) - 1952276..1953502 (-) 1227 WP_047920901.1 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 1033 a.a.        Molecular weight: 113474.87 Da        Isoelectric Point: 9.9336

>NTDB_id=735498 OCL42_RS10250 WP_263074895.1 1945431..1948532(+) (pilC) [Neisseria gonorrhoeae strain 10736]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGAMAQTYKYAIVMNAQNQPEVRWNGQYSTIKGKDREREYTYHNTRGGGGSV
SFNNTDTLVSQQSGTAVFGTATYLPPYGKVSGFDADALKERNNAVDWIRTTRIALAGYSYADVICKSSNQCPQLVYETKF
AFGQQGLQRKGNKLDIYEDKSRDNSPIYKLKDYPWLGVSFNLGSENTVKNSKSFNKLISSFNEDNNNQTIVSTTRDHPIS
LGNWQREHTAVAYYLNAKLHLLDKKRIEDIAQGKTVDLGTLRPRVETTGRGWLSFWARWDIKDTGQIPVKLGLPQVKAGR
CINKLNPNKNTKAPSPALTAPALWFGPGQDGKVQMYSASVSTYPDSSSSRIYLQNLKRKTEHGKPGRYSLVTLNENDIKS
RQPNFMGRQTIIRLDDGVHLIKLNGSKDEVVAFVNLNGNNTGKNDTFGIVKEANVNLDADEWKKVLLPWTVRGPGNDDKF
KSINQKPEKYSQRYRIRENGNRDLGDIVNSPIVAVGGYLATAANDGMVHIFKKNGGSDERSYNLKLSYIPGTMPRKDIES
KDSTLAKELRTFAEKGYVGDRYGVDGGFVLRQVELRGQKHVFMFGAMGLGGRGAYALDLSKINGNYPAAAPLFDVKNGDN
NGKNRVELGYTVGTPQIGKIRNGKYAAFLASGYAAKKIDGPTNTTALSTNTTALYVYDLNDTLGTPIAKIEVKDGKGGLS
SPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSDNDPNKWTVRTIFQGTKPITSAPAVSRLKDKRVVIFGTGSDLTEDDVLN
TDEQYIYGIFDDDKAANNVNASRGVLGSGLLEQHLTQENKTLFLNKRSDGSGSKGWAVKLTGGRRVTVKPTVVLRTAFVT
IRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPDNQVAQYSGHQKMNGKSVPIGCMWKNGKTVCPNGYVYDKPVNV
RYLDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3102 bp        

>NTDB_id=735498 OCL42_RS10250 WP_263074895.1 1945431..1948532(+) (pilC) [Neisseria gonorrhoeae strain 10736]
ATGAATAAAACTTTGAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACGTATAAATACGCTATTGTGATGAACGCGCAAAACCAGCCCGAGGTACGGTGGAATG
GGCAATATTCAACAATAAAGGGCAAAGACAGGGAGCGCGAATATACTTATCATAACACACGAGGAGGAGGAGGCTCTGTC
TCATTCAACAATACCGATACCCTTGTTTCCCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTA
CGGCAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCGTACCACCCGCATCG
CGCTGGCAGGCTACAGCTACGCCGACGTCATATGCAAAAGCAGCAACCAATGCCCCCAACTTGTCTATGAGACCAAATTT
GCCTTCGGTCAACAAGGGTTGCAAAGAAAGGGCAACAAGCTGGATATATACGAAGACAAAAGCCGCGACAATTCGCCCAT
TTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCAAATCAT
TCAACAAATTGATATCTTCTTTTAATGAAGACAATAATAATCAAACCATCGTCTCTACGACACGAGACCACCCTATTTCC
CTTGGCAACTGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAAGGAT
TGAAGATATCGCCCAAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAGGCTGGCTAA
GTTTTTGGGCTAGGTGGGACATTAAAGATACCGGGCAGATTCCGGTCAAGCTCGGCCTGCCGCAAGTCAAAGCAGGCCGC
TGCATCAACAAACTGAACCCCAATAAGAATACCAAAGCCCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGGACC
TGGGCAAGATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTACCTTC
AAAATCTGAAAAGAAAAACCGAACACGGCAAACCCGGCCGCTATTCCCTCGTAACCTTGAATGAGAATGATATTAAAAGT
CGACAGCCGAATTTCATGGGGCGGCAAACAATCATCCGATTGGATGACGGCGTACATTTGATCAAACTGAATGGAAGCAA
GGATGAGGTCGTCGCTTTTGTCAATTTAAATGGAAACAACACCGGCAAAAACGACACTTTCGGCATTGTTAAGGAAGCGA
ACGTCAATCTTGACGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGGTAATGACGATAAATTT
AAATCAATTAACCAAAAACCAGAAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAATCGCGATTTGGGCGACAT
CGTCAACAGCCCGATTGTCGCGGTCGGCGGGTATTTGGCAACCGCCGCGAACGACGGGATGGTGCATATCTTCAAAAAAA
ACGGCGGCAGTGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGTACGATGCCGCGCAAGGATATTGAAAGC
AAAGATTCTACACTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGG
CTTTGTCTTGCGCCAAGTCGAACTGCGCGGGCAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTGGGCGGCAGGGGCG
CGTATGCCTTGGATTTAAGCAAAATCAACGGAAATTATCCGGCCGCCGCTCCCCTGTTTGATGTCAAAAATGGCGATAAT
AACGGCAAAAATCGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAATCCGCAACGGCAAATACGCCGC
CTTCCTCGCCTCCGGTTATGCGGCTAAAAAAATTGACGGCCCAACAAATACAACCGCGCTGTCAACAAATACAACCGCGC
TGTATGTATATGATTTGAACGACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGAAGGACGGCAAGGGCGGGCTTTCG
TCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGGGGCGGGAATATGTACCG
CTTTGATTTGAGCGACAACGACCCGAACAAATGGACTGTACGCACTATTTTCCAAGGCACAAAACCGATTACTTCCGCGC
CCGCCGTTTCCCGACTGAAAGACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGACCGAAGATGATGTACTGAAT
ACGGACGAACAATATATTTACGGCATCTTCGACGACGATAAGGCGGCGAATAATGTAAATGCAAGCCGCGGCGTTTTGGG
GAGCGGGCTGCTCGAGCAACACCTTACTCAGGAAAATAAAACATTATTCCTGAACAAGAGATCCGACGGTTCGGGCAGCA
AGGGCTGGGCGGTGAAATTGACAGGCGGACGGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTAACC
ATCCGCAGCTATACGGGTAATGACAAATGTGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATT
GACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATAACCAGGTTGCGCAATATTCCGGCCATCAGAAAATGAACGGCAAGT
CCGTCCCCATAGGCTGCATGTGGAAAAACGGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTG
CGTTATCTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGC
CGGCAGGCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCT
TGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(504-845)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

75.19

100

0.766