Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | OCL42_RS02340 | Genome accession | NZ_CP106807 |
| Coordinates | 451879..452544 (+) | Length | 221 a.a. |
| NCBI ID | WP_263055817.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain 10736 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 450165..500179 | 451879..452544 | within | 0 |
Gene organization within MGE regions
Location: 450165..500179
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OCL42_RS02335 (OCL42_02335) | dnaB | 450165..451571 (+) | 1407 | WP_241532347.1 | replicative DNA helicase | - |
| OCL42_RS02340 (OCL42_02340) | pilH | 451879..452544 (+) | 666 | WP_263055817.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| OCL42_RS02345 (OCL42_02345) | pilI | 452573..453181 (+) | 609 | WP_033910489.1 | type IV pilus modification protein PilV | Machinery gene |
| OCL42_RS02350 (OCL42_02350) | pilJ | 453178..454146 (+) | 969 | WP_263074907.1 | PilW family protein | Machinery gene |
| OCL42_RS02355 (OCL42_02355) | pilK | 454125..454733 (+) | 609 | WP_215318018.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| OCL42_RS02360 (OCL42_02360) | pilL | 454735..455208 (+) | 474 | WP_260237126.1 | PilX family type IV pilin | Machinery gene |
| OCL42_RS02365 (OCL42_02365) | - | 455820..456265 (-) | 446 | Protein_463 | AzlC family ABC transporter permease | - |
| OCL42_RS02370 (OCL42_02370) | dut | 456431..456883 (+) | 453 | WP_260236890.1 | dUTP diphosphatase | - |
| OCL42_RS02375 (OCL42_02375) | dapC | 456961..458148 (+) | 1188 | WP_260236891.1 | succinyldiaminopimelate transaminase | - |
| OCL42_RS02380 (OCL42_02380) | yaaA | 458459..459238 (+) | 780 | WP_260236892.1 | peroxide stress protein YaaA | - |
| OCL42_RS02395 (OCL42_02395) | - | 459769..460961 (+) | 1193 | Protein_467 | tyrosine-type recombinase/integrase | - |
| OCL42_RS02400 (OCL42_02400) | - | 461316..461585 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| OCL42_RS02405 (OCL42_02405) | - | 461780..462463 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| OCL42_RS11840 | - | 462744..463010 (-) | 267 | Protein_470 | hypothetical protein | - |
| OCL42_RS02415 (OCL42_02415) | - | 463121..463336 (-) | 216 | WP_003693860.1 | hypothetical protein | - |
| OCL42_RS02420 (OCL42_02420) | - | 463388..463879 (-) | 492 | WP_263074863.1 | siphovirus Gp157 family protein | - |
| OCL42_RS02425 (OCL42_02425) | - | 463876..464058 (-) | 183 | WP_260236894.1 | hypothetical protein | - |
| OCL42_RS02430 (OCL42_02430) | - | 464198..464884 (-) | 687 | WP_263055815.1 | phage replication initiation protein, NGO0469 family | - |
| OCL42_RS02435 (OCL42_02435) | - | 464953..465114 (-) | 162 | WP_047924242.1 | hypothetical protein | - |
| OCL42_RS02440 (OCL42_02440) | - | 465111..465386 (-) | 276 | WP_003695501.1 | NGO1622 family putative holin | - |
| OCL42_RS02445 (OCL42_02445) | - | 465502..465834 (-) | 333 | WP_105183567.1 | hypothetical protein | - |
| OCL42_RS02450 (OCL42_02450) | - | 465973..466167 (-) | 195 | WP_003703103.1 | hypothetical protein | - |
| OCL42_RS02455 (OCL42_02455) | - | 466651..466869 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| OCL42_RS02460 (OCL42_02460) | - | 466886..467245 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| OCL42_RS02465 (OCL42_02465) | - | 467246..467785 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| OCL42_RS02470 (OCL42_02470) | - | 467945..468661 (-) | 717 | WP_003695999.1 | helix-turn-helix transcriptional regulator | - |
| OCL42_RS02475 (OCL42_02475) | - | 469042..469269 (+) | 228 | WP_050158909.1 | helix-turn-helix domain-containing protein | - |
| OCL42_RS02480 (OCL42_02480) | - | 469266..469403 (+) | 138 | WP_010359998.1 | hypothetical protein | - |
| OCL42_RS02485 (OCL42_02485) | - | 469387..470385 (+) | 999 | WP_050161100.1 | hypothetical protein | - |
| OCL42_RS02490 (OCL42_02490) | - | 470382..471743 (+) | 1362 | WP_260236895.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| OCL42_RS02495 (OCL42_02495) | - | 471760..472005 (+) | 246 | WP_260245438.1 | hypothetical protein | - |
| OCL42_RS02500 (OCL42_02500) | - | 472080..472574 (+) | 495 | WP_260236897.1 | DUF3310 domain-containing protein | - |
| OCL42_RS02505 (OCL42_02505) | - | 472752..472901 (+) | 150 | WP_003692854.1 | hypothetical protein | - |
| OCL42_RS02510 (OCL42_02510) | - | 472930..473211 (+) | 282 | WP_229691900.1 | hypothetical protein | - |
| OCL42_RS02515 (OCL42_02515) | - | 473202..473636 (+) | 435 | WP_260245439.1 | RusA family crossover junction endodeoxyribonuclease | - |
| OCL42_RS02520 (OCL42_02520) | - | 473629..473934 (+) | 306 | WP_053015205.1 | DUF1364 domain-containing protein | - |
| OCL42_RS02525 (OCL42_02525) | - | 473931..474314 (+) | 384 | WP_003687982.1 | recombination protein NinB | - |
| OCL42_RS02530 (OCL42_02530) | - | 474305..474823 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| OCL42_RS02535 (OCL42_02535) | - | 474888..475310 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| OCL42_RS02540 (OCL42_02540) | - | 475310..475849 (+) | 540 | WP_003693457.1 | hypothetical protein | - |
| OCL42_RS02545 (OCL42_02545) | - | 475830..477104 (+) | 1275 | WP_311201960.1 | PBSX family phage terminase large subunit | - |
| OCL42_RS02550 (OCL42_02550) | - | 477089..479356 (+) | 2268 | WP_263074909.1 | hypothetical protein | - |
| OCL42_RS02555 (OCL42_02555) | - | 479596..480120 (+) | 525 | WP_260236900.1 | hypothetical protein | - |
| OCL42_RS02560 (OCL42_02560) | - | 480117..480791 (+) | 675 | WP_260236901.1 | hypothetical protein | - |
| OCL42_RS02565 (OCL42_02565) | - | 480788..488554 (+) | 7767 | WP_263055812.1 | PLxRFG domain-containing protein | - |
| OCL42_RS02570 (OCL42_02570) | - | 488652..489059 (+) | 408 | WP_082298808.1 | hypothetical protein | - |
| OCL42_RS02575 (OCL42_02575) | - | 489070..489495 (+) | 426 | WP_106336882.1 | hypothetical protein | - |
| OCL42_RS02580 (OCL42_02580) | - | 489488..490375 (+) | 888 | WP_082298758.1 | hypothetical protein | - |
| OCL42_RS02585 (OCL42_02585) | - | 490375..490755 (+) | 381 | WP_082298757.1 | hypothetical protein | - |
| OCL42_RS02590 (OCL42_02590) | - | 490758..493964 (+) | 3207 | WP_260245440.1 | hypothetical protein | - |
| OCL42_RS02595 (OCL42_02595) | - | 493952..495145 (+) | 1194 | WP_134921505.1 | hypothetical protein | - |
| OCL42_RS02600 (OCL42_02600) | - | 495230..496129 (+) | 900 | WP_260236904.1 | hypothetical protein | - |
| OCL42_RS02610 (OCL42_02610) | - | 496150..497445 (+) | 1296 | Protein_509 | DUF4043 family protein | - |
| OCL42_RS02615 (OCL42_02615) | - | 497504..497977 (+) | 474 | WP_003693439.1 | hypothetical protein | - |
| OCL42_RS02620 (OCL42_02620) | - | 497983..498468 (+) | 486 | WP_003693438.1 | hypothetical protein | - |
| OCL42_RS02625 (OCL42_02625) | - | 498465..499139 (+) | 675 | WP_003693436.1 | hypothetical protein | - |
| OCL42_RS02630 (OCL42_02630) | - | 499142..499291 (+) | 150 | WP_017146863.1 | hypothetical protein | - |
| OCL42_RS02635 (OCL42_02635) | - | 499328..500179 (-) | 852 | WP_106336892.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 221 a.a. Molecular weight: 24532.77 Da Isoelectric Point: 9.1685
>NTDB_id=735467 OCL42_RS02340 WP_263055817.1 451879..452544(+) (pilH) [Neisseria gonorrhoeae strain 10736]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPAQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYAFNHIAFGSSQPTADRVVWTFNQNGTFGYSSD
QDLKNNSKFVYSDGYIQIVLTDARAVSDADRKFRSAVVLINSSGRVEVCRKNDTRAVCKHQ
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPAQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYAFNHIAFGSSQPTADRVVWTFNQNGTFGYSSD
QDLKNNSKFVYSDGYIQIVLTDARAVSDADRKFRSAVVLINSSGRVEVCRKNDTRAVCKHQ
Nucleotide
Download Length: 666 bp
>NTDB_id=735467 OCL42_RS02340 WP_263055817.1 451879..452544(+) (pilH) [Neisseria gonorrhoeae strain 10736]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TTTCCAGGGGCGAAGCCGTTCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTATGCCTTCAACCATATCG
CTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACGTTCAACCAAAACGGGACATTCGGCTATTCATCCGAT
CAGGATCTCAAGAATAATTCCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATCAATGA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TTTCCAGGGGCGAAGCCGTTCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTATGCCTTCAACCATATCG
CTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACGTTCAACCAAAACGGGACATTCGGCTATTCATCCGAT
CAGGATCTCAAGAATAATTCCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATCAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
94.545 |
99.548 |
0.941 |