Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   P7249_RS25870 Genome accession   NZ_CP120944
Coordinates   5198540..5199565 (+) Length   341 a.a.
NCBI ID   WP_000644904.1    Uniprot ID   P0ACN8
Organism   Escherichia coli O157:H7 str. EDL933     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5193540..5204565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P7249_RS25860 rpmE 5195771..5195983 (-) 213 WP_000710769.1 50S ribosomal protein L31 -
  P7249_RS25865 priA 5196186..5198384 (+) 2199 WP_001301674.1 primosomal protein N' Machinery gene
  P7249_RS25870 cytR 5198540..5199565 (+) 1026 WP_000644904.1 DNA-binding transcriptional regulator CytR Regulator
  P7249_RS25875 ftsN 5199657..5200616 (+) 960 WP_000068837.1 cell division protein FtsN -
  P7249_RS25880 hslV 5200709..5201239 (+) 531 WP_000208242.1 ATP-dependent protease subunit HslV -
  P7249_RS25885 hslU 5201249..5202580 (+) 1332 WP_001293341.1 HslU--HslV peptidase ATPase subunit -
  P7249_RS25890 menA 5202647..5203573 (+) 927 WP_001308187.1 1,4-dihydroxy-2-naphthoate polyprenyltransferase -
  P7249_RS25895 rraA 5203666..5204151 (+) 486 WP_000872908.1 ribonuclease E activity regulator RraA -

Sequence

Protein


Download         Length: 341 a.a.        Molecular weight: 37819.78 Da        Isoelectric Point: 6.3842

>NTDB_id=735393 P7249_RS25870 WP_000644904.1 5198540..5199565(+) (cytR) [Escherichia coli O157:H7 str. EDL933]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide


Download         Length: 1026 bp        

>NTDB_id=735393 P7249_RS25870 WP_000644904.1 5198540..5199565(+) (cytR) [Escherichia coli O157:H7 str. EDL933]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAAGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGTGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(11-56)

Periplasmic binding protein-like domain (Peripla_BP_3)

(176-337)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACN8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

64.179

98.24

0.63
  cytR Vibrio cholerae C6706

65.443

95.894

0.628