Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   LLE38_RS10960 Genome accession   NZ_CP106777
Coordinates   2078252..2079505 (+) Length   417 a.a.
NCBI ID   WP_003687004.1    Uniprot ID   A0AB74EGQ8
Organism   Neisseria gonorrhoeae strain 10727     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2073252..2084505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLE38_RS10940 (LLE38_10940) - 2074003..2075004 (+) 1002 WP_003686999.1 thiamine ABC transporter substrate-binding protein -
  LLE38_RS10945 (LLE38_10945) - 2075098..2075946 (+) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  LLE38_RS10950 (LLE38_10950) - 2075972..2076454 (+) 483 WP_003694396.1 CinA family protein -
  LLE38_RS10955 (LLE38_10955) msrAB 2076538..2078106 (-) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  LLE38_RS10960 (LLE38_10960) pilA 2078252..2079505 (+) 1254 WP_003687004.1 signal recognition particle-docking protein FtsY Machinery gene
  LLE38_RS10965 (LLE38_10965) - 2079571..2079762 (-) 192 WP_229940700.1 hypothetical protein -
  LLE38_RS10970 (LLE38_10970) - 2079776..2080588 (-) 813 WP_229940738.1 opacity family porin -
  LLE38_RS10975 (LLE38_10975) - 2081001..2081369 (-) 369 Protein_2116 pilin -
  LLE38_RS10980 (LLE38_10980) - 2081409..2081765 (-) 357 Protein_2117 pilin -
  LLE38_RS10985 (LLE38_10985) - 2081805..2082197 (-) 393 Protein_2118 pilin -
  LLE38_RS10990 (LLE38_10990) pilE 2082756..2083166 (-) 411 WP_229940731.1 pilin Machinery gene
  LLE38_RS10995 (LLE38_10995) lpxC 2083272..2084195 (-) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44389.74 Da        Isoelectric Point: 4.8123

>NTDB_id=734957 LLE38_RS10960 WP_003687004.1 2078252..2079505(+) (pilA) [Neisseria gonorrhoeae strain 10727]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=734957 LLE38_RS10960 WP_003687004.1 2078252..2079505(+) (pilA) [Neisseria gonorrhoeae strain 10727]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGGTTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTCATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATGCGGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATCATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGTCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.76

100

0.998