Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LLE38_RS00265 Genome accession   NZ_CP106777
Coordinates   52663..55782 (-) Length   1039 a.a.
NCBI ID   WP_229940669.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 10727     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47663..60782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLE38_RS00245 (LLE38_00245) - 49066..49455 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  LLE38_RS00255 (LLE38_00255) - 49618..49997 (-) 380 Protein_48 VOC family protein -
  LLE38_RS00260 (LLE38_00260) carA 50051..51184 (-) 1134 WP_003699436.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  LLE38_RS00265 (LLE38_00265) pilC 52663..55782 (-) 3120 WP_229940669.1 PilC family type IV pilus tip adhesin Machinery gene
  LLE38_RS00270 (LLE38_00270) apbC 57227..58306 (-) 1080 WP_003699443.1 iron-sulfur cluster carrier protein ApbC -
  LLE38_RS00280 (LLE38_00280) - 58680..59189 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  LLE38_RS00285 (LLE38_00285) nadR 59530..59970 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  LLE38_RS00290 (LLE38_00290) hpaC 60085..60585 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1039 a.a.        Molecular weight: 114381.88 Da        Isoelectric Point: 9.8685

>NTDB_id=734911 LLE38_RS00265 WP_229940669.1 52663..55782(-) (pilC) [Neisseria gonorrhoeae strain 10727]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAETREYAIIMNGRNQPEVKSNVPYSIKDKDRKRVFDYTSQKSSLGGTNN
FISFNNNDEVVARKNGTAVFGTATYLPPYGKVSGFDADALKERANAVDWIRTTRPGLAGYAYTDVICRDAEQCPQLVYET
KFAFGQQGLQRNGNKLDIYEDKSRDNSPIYKLKDYPWLGVSFNLGSENTVKNGRSSGRLISSFSENNNNQTIVSTTRDRP
ISLGDRQREHTAVAYYLNAKLHLLDKKRIKDIAQGKTVDLGTLRPRVETTGRNWLSYWATWKIEDKGNITVRLGLPEVKA
GRCINKPNPNPKSALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSRIFLQELKTKTDPGRPGRHSLAALNERDIK
SREPNFNSRQTVIRLPGGVYRIAPGNSGRVAGFNDNDGKNDTFGIYKDRLVIPEPDEWSEVLLPWTARYYGNDDIFKTFN
QPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATAANDGMVHLFKRNGTDQRGYELKLSYIPGTM
PRQYFDNDTSALKDSTLAQELRTFAEKGYVGDRYGVDGGFVLRRITDDQDRQKLFFMFGAMGLGGRGAYALDLTKIDNSN
LTGVSMFDVKNESKNNGVKLGYTVGTPQIGKIRNGKYAAFLASGYAAKDIVSSDNTTALYVYDLGNGGGSLIKKIEAPGG
KGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSGDNPSKWTVRTIFQGTKPITSAPAVSRLADKRVVIFGTGSDLSE
QDVVDKDQQYIYGIFDDDKGTVKVTVQNGTGGGLLEQVLKEENKTLFLNKGSDGSGSKGWVVKLKEGQRVTVKPTVVLRT
AFVTIRKYKDDGCGADTAILGINTADGGALTPRSARPIVPEANKDVAQYSGHKTTSKGKSIPIGCMEKGGKTVCPNGYVY
DKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3120 bp        

>NTDB_id=734911 LLE38_RS00265 WP_229940669.1 52663..55782(-) (pilC) [Neisseria gonorrhoeae strain 10727]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGGAAACCCGTGAATACGCTATTATCATGAACGGGCGAAACCAGCCCGAGGTAAAGTCGAATGTGC
CATATTCAATAAAGGACAAAGACAGGAAGCGGGTATTTGACTATACGAGCCAGAAAAGCAGCTTAGGCGGGACAAACAAT
TTTATCTCATTCAACAATAACGATGAAGTTGTTGCTCGAAAAAACGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCC
GCCCTACGGCAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCGCCAATGCCGTTGATTGGATTCGTACCACCC
GGCCCGGGCTGGCAGGCTACGCCTACACCGACGTCATATGCAGAGACGCAGAGCAATGCCCCCAACTTGTCTATGAGACC
AAATTTGCCTTCGGTCAACAAGGGTTGCAAAGAAATGGCAACAAGCTGGATATATACGAAGACAAAAGCCGCGACAATTC
GCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATGGCA
GATCATCCGGCAGATTGATATCTTCTTTTAGTGAAAACAATAATAATCAAACCATCGTCTCTACGACACGAGACCGCCCT
ATTTCCCTTGGCGACCGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCACCTGCTGGACAAAAA
AAGGATTAAAGATATCGCCCAAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAACT
GGCTAAGTTATTGGGCTACGTGGAAGATTGAAGATAAAGGGAACATTACAGTCCGCCTCGGCCTGCCGGAAGTCAAAGCA
GGCCGCTGCATCAACAAACCGAACCCCAATCCCAAATCAGCCCTTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGG
CCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCCGCATCTTCC
TCCAAGAGCTGAAAACTAAAACCGACCCCGGCAGGCCCGGCCGGCATTCCCTCGCCGCTTTGAATGAACGAGATATCAAA
TCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGGCGTGTACCGGATCGCCCCGGGCAATAG
CGGCCGGGTCGCGGGTTTTAATGACAATGACGGCAAAAACGACACTTTCGGCATCTACAAGGACAGGCTCGTCATACCTG
AGCCCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACGGCCCGGTATTACGGTAATGACGATATATTTAAAACATTCAAC
CAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCGCATCCGCACAAAAGAAGATGACAATGA
CAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCGGCGGGTATCTGGCAACCGCCGCGAACGACG
GGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAACTGAAGCTCAGCTACATCCCCGGCACGATG
CCGCGCCAATATTTTGATAACGACACTTCCGCTCTCAAAGACTCCACCCTCGCCCAAGAGCTGCGCACCTTTGCCGAAAA
AGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAGGACAGGCAAAAAC
TTTTCTTTATGTTTGGTGCGATGGGCCTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAATCGACAACAGCAAC
CTGACCGGCGTTTCCATGTTTGATGTCAAAAACGAGAGTAAAAATAATGGCGTGAAATTAGGCTACACCGTCGGTACGCC
GCAAATCGGCAAAATCCGCAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAAGATATTGTCAGCAGCG
ATAATACAACCGCGCTGTATGTGTATGATTTGGGAAACGGCGGTGGTAGTCTGATTAAAAAAATCGAAGCACCCGGCGGC
AAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGG
CGGCAATATGTACCGCTTTGATTTGAGCGGCGACAATCCGTCCAAATGGACTGTACGCACTATTTTCCAAGGCACAAAAC
CGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTGGTCATCTTCGGTACGGGCAGCGATTTGAGTGAA
CAGGATGTAGTCGATAAGGATCAACAATATATTTACGGTATCTTTGACGACGATAAGGGGACGGTTAAGGTAACGGTACA
AAACGGCACGGGAGGCGGGCTGCTCGAGCAAGTGCTTAAAGAGGAAAATAAAACATTATTCCTGAACAAGGGATCCGACG
GATCGGGCAGTAAGGGGTGGGTAGTGAAGCTGAAGGAAGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACC
GCCTTCGTAACCATCCGCAAGTATAAAGACGACGGCTGCGGCGCGGATACCGCCATTTTGGGCATCAATACCGCCGACGG
CGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGAAGCCAATAAGGATGTCGCACAATATTCCGGCCATAAGA
CAACCTCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGGCGGTAAAACCGTCTGCCCGAACGGATATGTTTAC
GACAAGCCGGTTAATGTGCGTTATCTGGACGAAAAGAAAACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGG
CAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGA
TGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(512-848)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.46

100

0.734