Detailed information NTG0733978

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: N7985_RS12745
• Genome accession: NZ_CP106673
• Coordinates: 2485228..2487558 (-)
• Length: 776 a.a.
• NCBI ID: WP_041850028.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain SRCM116268
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2480228..2492558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N7985_RS12710 (N7985_12710)	yqxA	2480567..2480905 (-)	339	WP_041850027.1	YqxA family protein	-
N7985_RS12715 (N7985_12715)	spoIIP	2480922..2482127 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
N7985_RS12720 (N7985_12720)	gpr	2482190..2483296 (-)	1107	WP_014480309.1	GPR endopeptidase	-
N7985_RS12725 (N7985_12725)	rpsT	2483500..2483766 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
N7985_RS12730 (N7985_12730)	holA	2483781..2484824 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
N7985_RS12735 (N7985_12735)	-	2484864..2485013 (-)	150	WP_120363468.1	hypothetical protein	-
N7985_RS12740 (N7985_12740)	yqzM	2485054..2485188 (+)	135	WP_003229983.1	YqzM family protein	-
N7985_RS12745 (N7985_12745)	comEC	2485228..2487558 (-)	2331	WP_041850028.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
N7985_RS12750 (N7985_12750)	comEB	2487562..2488131 (-)	570	WP_003229978.1	ComE operon protein 2	-
N7985_RS12755 (N7985_12755)	comEA	2488198..2488815 (-)	618	WP_041850029.1	competence protein ComEA	Machinery gene
N7985_RS12760 (N7985_12760)	comER	2488899..2489720 (+)	822	WP_041850030.1	late competence protein ComER	-
N7985_RS12765 (N7985_12765)	yqeM	2489786..2490529 (-)	744	WP_032726197.1	class I SAM-dependent methyltransferase	-
N7985_RS12770 (N7985_12770)	rsfS	2490526..2490882 (-)	357	WP_003237112.1	ribosome silencing factor	-
N7985_RS12775 (N7985_12775)	yqeK	2490900..2491460 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
N7985_RS12780 (N7985_12780)	nadD	2491450..2492019 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
N7985_RS12785 (N7985_12785)	yhbY	2492031..2492321 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86739.47 Da
• Isoelectric Point: 7.4973

>NTDB_id=733978 N7985_RS12745 WP_041850028.1 2485228..2487558(-) (comEC) [Bacillus subtilis strain SRCM116268]
MRNSRLLLPMAAASATVGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIATIPKIDGDRMSMMVKTPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPKHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITKIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVLFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKMLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGVLSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=733978 N7985_RS12745 WP_041850028.1 2485228..2487558(-) (comEC) [Bacillus subtilis strain SRCM116268]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGTTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGCCACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAAACACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTCAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTGCTGCCTCCTGATTCGGCAGGAATTGTACAGGCACTTACAGTCGGTGACAGAT
TTTATGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATCCGCCTTGGTATAACAAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGTCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGTTAATCACAAAAATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTCTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGCGGC
ATTTGCTGCACAGTGCTGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGATGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
GCACCTGATCCGGCAAGCAAAAATAATTCATCTCTCGTTCTGTGGATGGAGACGGGCGTTCTGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	97.809	100	0.978