Detailed information NTG0073386

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: GOZ34_RS13165
• Genome accession: NZ_AP019712
• Coordinates: 2665981..2666868 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain Tokyo12480
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2660981..2671868

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOZ34_RS13135	-	2660989..2661081 (+)	93	WP_031774855.1	hypothetical protein	-
GOZ34_RS13140 (TMSFP480_24780)	-	2661189..2661686 (-)	498	WP_155978349.1	glutathione peroxidase	-
GOZ34_RS13145 (TMSFP480_24790)	-	2661696..2661956 (-)	261	WP_001791293.1	hypothetical protein	-
GOZ34_RS13150	-	2662338..2662451 (-)	114	WP_014937089.1	hypothetical protein	-
GOZ34_RS13155 (TMSFP480_24800)	-	2663121..2665121 (-)	2001	WP_000776741.1	ABC transporter permease	-
GOZ34_RS13160 (TMSFP480_24810)	-	2665118..2665873 (-)	756	WP_072460436.1	ABC transporter ATP-binding protein	-
GOZ34_RS13165 (TMSFP480_24820)	braS	2665981..2666868 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
GOZ34_RS13170 (TMSFP480_24830)	braR	2666879..2667544 (-)	666	WP_155978350.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
GOZ34_RS13175 (TMSFP480_24840)	-	2667570..2667770 (-)	201	WP_070974005.1	hypothetical protein	-
GOZ34_RS13180 (TMSFP480_24850)	-	2667968..2669392 (+)	1425	WP_072460435.1	alkaline phosphatase	-
GOZ34_RS13855	-	2669452..2669553 (-)	102	WP_000731972.1	SE2200 family small protein	-
GOZ34_RS13190 (TMSFP480_24860)	-	2669675..2670130 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
GOZ34_RS13195 (TMSFP480_24870)	-	2670374..2671135 (-)	762	WP_070974003.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=73386 GOZ34_RS13165 WP_000143420.1 2665981..2666868(-) (braS) [Staphylococcus aureus strain Tokyo12480]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=73386 GOZ34_RS13165 WP_000143420.1 2665981..2666868(-) (braS) [Staphylococcus aureus strain Tokyo12480]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993