Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   GOZ34_RS10145 Genome accession   NZ_AP019712
Coordinates   2062523..2063239 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain Tokyo12480     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2057523..2068239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOZ34_RS10115 (TMSFP480_19140) - 2057738..2058364 (+) 627 WP_000522384.1 nitroreductase family protein -
  GOZ34_RS10120 (TMSFP480_19150) - 2058725..2059510 (+) 786 WP_155978250.1 carbon-nitrogen family hydrolase -
  GOZ34_RS13845 hld 2060111..2060191 (-) 81 WP_000046022.1 delta-hemolysin -
  GOZ34_RS10130 (TMSFP480_19170) agrB 2060481..2061050 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  GOZ34_RS10135 (TMSFP480_19180) agrD 2061047..2061187 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  GOZ34_RS10140 (TMSFP480_19190) agrC 2061212..2062504 (+) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  GOZ34_RS10145 (TMSFP480_19200) agrA 2062523..2063239 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  GOZ34_RS10150 (TMSFP480_19210) - 2063613..2064572 (-) 960 WP_155978251.1 carbohydrate kinase family protein -
  GOZ34_RS10155 (TMSFP480_19220) - 2064569..2066053 (-) 1485 WP_029550166.1 sucrose-6-phosphate hydrolase -
  GOZ34_RS10160 (TMSFP480_19230) - 2066202..2067152 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=73382 GOZ34_RS10145 WP_000688492.1 2062523..2063239(+) (agrA) [Staphylococcus aureus strain Tokyo12480]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=73382 GOZ34_RS10145 WP_000688492.1 2062523..2063239(+) (agrA) [Staphylococcus aureus strain Tokyo12480]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment