Detailed information NTG0073380

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: GOZ34_RS09415
• Genome accession: NZ_AP019712
• Coordinates: 1942292..1943335 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Tokyo12480
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1937292..1948335

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOZ34_RS09385 (TMSFP480_17730)	-	1937713..1938969 (-)	1257	WP_001793428.1	aminopeptidase	-
GOZ34_RS09390 (TMSFP480_17740)	-	1938972..1939172 (-)	201	WP_000180460.1	DUF1128 family protein	-
GOZ34_RS09395 (TMSFP480_17750)	-	1939319..1939783 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
GOZ34_RS09400 (TMSFP480_17760)	-	1939790..1940065 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
GOZ34_RS09405 (TMSFP480_17770)	-	1940343..1941560 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
GOZ34_RS09410 (TMSFP480_17780)	vraR	1941673..1942302 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
GOZ34_RS09415 (TMSFP480_17790)	vraS	1942292..1943335 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
GOZ34_RS09420 (TMSFP480_17800)	liaF	1943332..1944033 (-)	702	WP_029550141.1	cell wall-active antibiotics response protein LiaF	-
GOZ34_RS09425 (TMSFP480_17810)	-	1944048..1944434 (-)	387	WP_029550142.1	hypothetical protein	-
GOZ34_RS09430 (TMSFP480_17820)	map	1944651..1945409 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
GOZ34_RS09435 (TMSFP480_17830)	-	1945824..1946810 (+)	987	WP_155978236.1	FUSC family protein	-
GOZ34_RS09440 (TMSFP480_17840)	-	1946999..1947412 (-)	414	WP_155978394.1	hypothetical protein	-
GOZ34_RS09445	-	1947441..1947551 (-)	111	WP_072512335.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=73380 GOZ34_RS09415 WP_001017131.1 1942292..1943335(-) (vraS) [Staphylococcus aureus strain Tokyo12480]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=73380 GOZ34_RS09415 WP_001017131.1 1942292..1943335(-) (vraS) [Staphylococcus aureus strain Tokyo12480]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1