Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   P3L36_RS10205 Genome accession   NZ_CP120654
Coordinates   2025635..2026969 (-) Length   444 a.a.
NCBI ID   WP_001089365.1    Uniprot ID   Q8L360
Organism   Streptococcus agalactiae strain Guangzhou-SAG036     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2020635..2031969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3L36_RS10175 (P3L36_10175) - 2020908..2021333 (-) 426 WP_000823121.1 PTS mannose transporter subunit IIA -
  P3L36_RS10180 (P3L36_10180) - 2021580..2022614 (-) 1035 WP_000369170.1 acyltransferase family protein -
  P3L36_RS10185 (P3L36_10185) - 2022843..2023997 (-) 1155 WP_050151858.1 ABC transporter permease subunit -
  P3L36_RS10190 (P3L36_10190) - 2024003..2024851 (-) 849 WP_000926585.1 ABC transporter ATP-binding protein -
  P3L36_RS10195 (P3L36_10195) - 2024920..2025093 (-) 174 WP_000683602.1 hypothetical protein -
  P3L36_RS10200 (P3L36_10200) - 2025382..2025546 (+) 165 Protein_1939 cysteine peptidase family C39 domain-containing protein -
  P3L36_RS10205 (P3L36_10205) comD/blpH 2025635..2026969 (-) 1335 WP_001089365.1 GHKL domain-containing protein Regulator
  P3L36_RS10210 (P3L36_10210) comE/blpR 2026966..2027718 (-) 753 WP_001019938.1 LytTR family DNA-binding domain-containing protein Regulator
  P3L36_RS10215 (P3L36_10215) - 2027934..2028749 (-) 816 WP_001029871.1 endonuclease/exonuclease/phosphatase family protein -
  P3L36_RS10220 (P3L36_10220) - 2028803..2030986 (-) 2184 WP_000795059.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 51259.05 Da        Isoelectric Point: 8.2893

>NTDB_id=733779 P3L36_RS10205 WP_001089365.1 2025635..2026969(-) (comD/blpH) [Streptococcus agalactiae strain Guangzhou-SAG036]
MNSTLSILEIALTIILTIFLFSKISGRQLTLIEIGICIALRLGLVILFIAANTIINLSFLKYWLLPIYMLSLAFLLLRPI
SKTLVVFYGLFPIVLRNLCSRSLAFFVFPLFNIDFHTTNQGFWGYFVDVLSTLCVLLFLRWMQYDFKTLRSSEVSPIDKR
ILQFTNGCMVSYYLLMQFSTYLEYELAINTVIYRQFLLVVYWIIFTGAIASLDRRLRNSLQERLAVQRELQLANMIDYSH
HIEGLYKEVRSFRHDYSNMLTTLKLGIDNEDISIVKSVYQSIFKESNTHFRHPKYNIDRLVNVDNPALKSLLAAKLSQAI
DNHIMVSIEVPDSIKPQGMELIDFITIVSVLWDNAIEASLETDDPKIAMSYFTLKHKQIFIIENSTKEKAIDTSTIFNYE
ISSKGRNRGIGLYNVRGVINRYPNISIATSSQDFSFCQTFEIIL

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=733779 P3L36_RS10205 WP_001089365.1 2025635..2026969(-) (comD/blpH) [Streptococcus agalactiae strain Guangzhou-SAG036]
ATGAATTCTACTCTATCCATCTTAGAGATAGCTTTAACGATAATATTAACAATATTTCTCTTTTCTAAAATCAGTGGACG
TCAATTGACTTTAATAGAGATTGGAATTTGTATTGCTCTGAGATTAGGACTTGTAATTTTATTTATAGCAGCTAATACTA
TTATTAATCTTTCATTTCTAAAGTACTGGCTTCTCCCCATCTATATGTTAAGTCTGGCTTTCTTGTTGCTAAGACCTATA
TCTAAAACTTTAGTAGTCTTTTATGGCTTGTTTCCAATTGTTCTCAGAAATCTTTGTTCACGTTCTTTAGCTTTTTTTGT
CTTTCCTTTGTTTAATATTGATTTTCATACAACCAACCAGGGGTTTTGGGGATATTTTGTTGATGTCTTGTCTACTCTTT
GTGTTCTCCTATTTTTAAGATGGATGCAATACGACTTTAAAACTTTGCGAAGTAGTGAAGTTTCGCCCATAGATAAGAGA
ATTCTCCAATTTACGAATGGTTGTATGGTCAGTTATTACTTACTGATGCAGTTTTCAACTTATTTGGAATATGAATTAGC
CATCAATACTGTTATTTACCGGCAATTTTTGCTTGTTGTTTATTGGATTATATTTACGGGAGCAATAGCCAGTTTAGACC
GGAGACTTCGAAATTCTTTACAGGAGAGGTTAGCTGTTCAAAGAGAACTCCAATTGGCTAATATGATAGATTATAGCCAC
CATATTGAGGGGTTGTATAAAGAAGTTAGGAGCTTCCGACATGATTATAGTAACATGTTAACGACCTTGAAACTAGGGAT
TGATAATGAAGATATATCTATTGTCAAATCAGTTTATCAGTCTATCTTTAAAGAATCTAATACACATTTCCGACATCCTA
AGTATAATATAGACCGGTTGGTTAATGTAGATAACCCAGCCTTAAAAAGTCTTTTAGCAGCCAAGCTTTCACAAGCGATA
GACAATCATATTATGGTATCTATAGAAGTACCAGACAGTATTAAACCTCAAGGGATGGAACTGATTGATTTTATTACCAT
TGTATCTGTTTTATGGGATAACGCTATTGAGGCATCTTTAGAGACAGACGATCCTAAGATAGCCATGTCTTATTTTACAT
TAAAACATAAACAAATTTTTATCATAGAAAATTCAACTAAGGAAAAGGCAATAGATACGTCAACGATATTCAATTATGAG
ATAAGTAGTAAGGGGCGGAATAGAGGAATAGGTCTTTACAATGTCAGGGGAGTTATCAATCGTTATCCAAATATTTCTAT
TGCAACAAGTAGCCAAGATTTTAGTTTCTGCCAAACTTTCGAAATCATATTATAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(339-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8L360

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

35.903

100

0.367