Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   P3L36_RS02215 Genome accession   NZ_CP120654
Coordinates   377469..378110 (+) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain Guangzhou-SAG036     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 372469..383110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3L36_RS02195 (P3L36_02195) - 372914..373651 (+) 738 WP_000406233.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  P3L36_RS02200 (P3L36_02200) pknB 373651..375606 (+) 1956 WP_071664833.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  P3L36_RS02205 (P3L36_02205) liaF 375765..376460 (+) 696 WP_277687541.1 cell wall-active antibiotics response protein LiaF -
  P3L36_RS02210 (P3L36_02210) - 376457..377476 (+) 1020 WP_000716168.1 sensor histidine kinase -
  P3L36_RS02215 (P3L36_02215) vraR 377469..378110 (+) 642 WP_000357891.1 response regulator transcription factor Regulator
  P3L36_RS02220 (P3L36_02220) - 378152..379552 (+) 1401 WP_000339135.1 Cof-type HAD-IIB family hydrolase -
  P3L36_RS02225 (P3L36_02225) - 379554..379910 (+) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  P3L36_RS02230 (P3L36_02230) - 379956..380732 (-) 777 WP_000180538.1 glycyl-radical enzyme activating protein -
  P3L36_RS02235 (P3L36_02235) - 380853..381608 (+) 756 WP_001080743.1 DeoR/GlpR family DNA-binding transcription regulator -
  P3L36_RS02240 (P3L36_02240) - 381727..382710 (+) 984 WP_000764461.1 sugar-binding transcriptional regulator -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=733712 P3L36_RS02215 WP_000357891.1 377469..378110(+) (vraR) [Streptococcus agalactiae strain Guangzhou-SAG036]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=733712 P3L36_RS02215 WP_000357891.1 377469..378110(+) (vraR) [Streptococcus agalactiae strain Guangzhou-SAG036]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAAGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCACTGGAGTTACGTCCAGACGTTGTTG
TTATGGATTTAGTAATGCCTGAAATGGACGGTGTAGAAGCAACCTTAGCATTGTTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGACAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGTGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATCCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTGGCAGATCGAACTCAAGCGGTTGTCTATGCTTTCCAACACCATTTGGTACCACAAGATGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394