Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   P5649_RS17685 Genome accession   NZ_CP120613
Coordinates   3376081..3377964 (-) Length   627 a.a.
NCBI ID   WP_003245099.1    Uniprot ID   P49850
Organism   Bacillus subtilis strain DSM 23521     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3371081..3382964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5649_RS17655 (P5649_17655) fabD 3371672..3372538 (-) 867 WP_003231821.1 ACP S-malonyltransferase -
  P5649_RS17660 (P5649_17660) - 3372535..3372801 (-) 267 WP_019712693.1 hypothetical protein -
  P5649_RS17665 (P5649_17665) pksB 3372911..3373588 (-) 678 WP_003231824.1 MBL fold metallo-hydrolase -
  P5649_RS17670 (P5649_17670) pksA 3373778..3374395 (-) 618 WP_003231827.1 TetR/AcrR family transcriptional regulator -
  P5649_RS17675 (P5649_17675) - 3374516..3375073 (+) 558 WP_003245720.1 hypothetical protein -
  P5649_RS17680 (P5649_17680) ymzD 3375228..3375683 (+) 456 WP_003231830.1 regulatory YrvL family protein -
  P5649_RS17685 (P5649_17685) hexB 3376081..3377964 (-) 1884 WP_003245099.1 DNA mismatch repair endonuclease MutL Machinery gene
  P5649_RS17690 (P5649_17690) hexA 3377980..3380556 (-) 2577 WP_003244841.1 DNA mismatch repair protein MutS Machinery gene
  P5649_RS17695 (P5649_17695) cotE 3380689..3381234 (-) 546 WP_003231833.1 outer spore coat protein CotE -
  P5649_RS17700 (P5649_17700) ymcA 3381496..3381927 (-) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70431.38 Da        Isoelectric Point: 5.8680

>NTDB_id=733166 P5649_RS17685 WP_003245099.1 3376081..3377964(-) (hexB) [Bacillus subtilis strain DSM 23521]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQVPKKSAPAIKNEQQFITFDEKPPEKKVPEKSTAPSYSPMKLSSVVKEPVDAEEKLPPLQFDAPPI
VDQEQTLEVSDVSAEQPETFEQECHEEQPQPASDRVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQEMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=733166 P5649_RS17685 WP_003245099.1 3376081..3377964(-) (hexB) [Bacillus subtilis strain DSM 23521]
GTGGCAAAAGTCATCCAACTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGGCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACAGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATACGTGACGGA
ATTAAAGATGTGTTTAAACAGCAGCAGCTGATTCCTAGTGCCCAGGTCCCGAAAAAATCAGCACCTGCCATCAAAAATGA
GCAGCAGTTTATAACCTTTGATGAAAAGCCTCCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGCCATCTTATTCACCGA
TGAAGCTCAGCTCAGTCGTAAAAGAGCCGGTTGATGCGGAGGAAAAATTGCCCCCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGCAGAACAGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCCGCAGCCAGCGTCTGATCGGGTTCCAATTATGTACCCGATTGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTATATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTCCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGAGATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCAG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTTCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(442-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3GAB
  PDB 3KDG
  PDB 3KDK
  PDB 6E8D

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.497

100

0.467