Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   P5622_RS00270 Genome accession   NZ_CP120598
Coordinates   50626..51267 (-) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain PRO115     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 45626..56267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5622_RS00255 (P5622_00255) ydfK 46131..46820 (+) 690 WP_003242513.1 DUF554 domain-containing protein -
  P5622_RS00260 (P5622_00260) cesA 47022..47924 (+) 903 WP_003242638.1 carboxylesterase -
  P5622_RS00265 (P5622_00265) ydfJ 48336..50510 (-) 2175 WP_003243548.1 MMPL family transporter -
  P5622_RS00270 (P5622_00270) vraR 50626..51267 (-) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  P5622_RS00275 (P5622_00275) ydfH 51260..52483 (-) 1224 WP_010886422.1 two-component system sensor histidine kinase YdfH -
  P5622_RS00280 (P5622_00280) - 52751..52894 (+) 144 WP_003243880.1 hypothetical protein -
  P5622_RS00285 (P5622_00285) - 52891..53070 (+) 180 WP_010886421.1 hypothetical protein -
  P5622_RS00290 (P5622_00290) ydfG 53156..53599 (+) 444 WP_003242768.1 carboxymuconolactone decarboxylase family protein -
  P5622_RS00295 (P5622_00295) ydfF 53679..54359 (-) 681 WP_003244115.1 winged helix-turn-helix domain-containing protein -
  P5622_RS00300 (P5622_00300) ydfE 54449..55072 (+) 624 WP_003243530.1 flavin reductase family protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=732767 P5622_RS00270 WP_003244318.1 50626..51267(-) (vraR) [Bacillus subtilis strain PRO115]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=732767 P5622_RS00270 WP_003244318.1 50626..51267(-) (vraR) [Bacillus subtilis strain PRO115]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTAGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362