Detailed information NTG0732623

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: P5628_RS00435
• Genome accession: NZ_CP120577
• Coordinates: 77287..78369 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain PRO53
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 72287..83369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P5628_RS00420 (P5628_00420)	mcsB	72295..73386 (+)	1092	WP_003235007.1	protein arginine kinase	-
P5628_RS00425 (P5628_00425)	clpC	73383..75815 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
P5628_RS00430 (P5628_00430)	radA/sms	75907..77283 (+)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
P5628_RS00435 (P5628_00435)	disA	77287..78369 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
P5628_RS00440 (P5628_00440)	yacL	78485..79585 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
P5628_RS00445 (P5628_00445)	ispD	79600..80298 (+)	699	WP_041850244.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
P5628_RS00450 (P5628_00450)	ispF	80291..80767 (+)	477	WP_038827792.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
P5628_RS00455 (P5628_00455)	gltX	80858..82309 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
P5628_RS00460 (P5628_00460)	cysE	82611..83264 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=732623 P5628_RS00435 WP_003225736.1 77287..78369(+) (disA) [Bacillus subtilis strain PRO53]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=732623 P5628_RS00435 WP_003225736.1 77287..78369(+) (disA) [Bacillus subtilis strain PRO53]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCTACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTTAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTCCTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGACATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCTGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAGGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1