Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   P5708_RS24295 Genome accession   NZ_CP120563
Coordinates   4975187..4976179 (-) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli strain H22     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4970187..4981179
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5708_RS24285 (P5708_24285) yieP 4973079..4973771 (+) 693 WP_277698213.1 FadR/GntR family transcriptional regulator -
  P5708_RS24290 (P5708_24290) mdtD 4973794..4975221 (+) 1428 WP_001280828.1 multidrug transporter subunit MdtD -
  P5708_RS24295 (P5708_24295) cytR 4975187..4976179 (-) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  P5708_RS24300 (P5708_24300) rbsK 4976183..4977112 (-) 930 WP_001361088.1 ribokinase -
  P5708_RS24305 (P5708_24305) rbsB 4977238..4978128 (-) 891 WP_001297966.1 ribose ABC transporter substrate-binding protein RbsB -
  P5708_RS24310 (P5708_24310) rbsC 4978153..4979118 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  P5708_RS24315 (P5708_24315) rbsA 4979123..4980628 (-) 1506 WP_000387770.1 ribose ABC transporter ATP-binding protein RbsA -
  P5708_RS24320 (P5708_24320) rbsD 4980636..4981055 (-) 420 WP_001314250.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=732448 P5708_RS24295 WP_000224470.1 4975187..4976179(-) (cytR) [Escherichia coli strain H22]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=732448 P5708_RS24295 WP_000224470.1 4975187..4976179(-) (cytR) [Escherichia coli strain H22]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACAGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTTGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGTAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAGCCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACCGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATTGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCTGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCTATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACAACTATACACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTACAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGTGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364