Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NDL69_RS10270 Genome accession   NZ_CP104548
Coordinates   1933976..1937086 (+) Length   1036 a.a.
NCBI ID   WP_267720151.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 10538     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1928976..1942086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NDL69_RS10250 (NDL69_10165) - 1929673..1930122 (-) 450 WP_003692085.1 CopD family copper resistance protein -
  NDL69_RS10255 (NDL69_10170) waaA 1930163..1931434 (-) 1272 WP_010360974.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  NDL69_RS10260 (NDL69_10175) gnd 1931497..1932945 (-) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  NDL69_RS10265 (NDL69_10180) - 1933025..1933288 (-) 264 WP_017147189.1 hypothetical protein -
  NDL69_RS10270 (NDL69_10185) pilC 1933976..1937086 (+) 3111 WP_267720151.1 PilC family type IV pilus tip adhesin Machinery gene
  NDL69_RS10275 (NDL69_10190) - 1937739..1938023 (+) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  NDL69_RS10280 (NDL69_10195) yccS 1938507..1940657 (-) 2151 WP_003697785.1 YccS family putative transporter -
  NDL69_RS10285 (NDL69_10200) - 1940774..1942000 (-) 1227 WP_003697786.1 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 1036 a.a.        Molecular weight: 113402.80 Da        Isoelectric Point: 9.9355

>NTDB_id=730389 NDL69_RS10270 WP_267720151.1 1933976..1937086(+) (pilC) [Neisseria gonorrhoeae strain 10538]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGGAMAQTRQYAIVMNKRNQPEVKWDGQYQKSQLREKDGERKFIYTNQRNKL
GQQNNFISFDNTDELVSRQSGTAVFGTATYLPPYGKVSGFDTDRLKKRNNAVDWIRTTRIALAGYSYEGVVCRSGTGCPK
LVYKTRFSFDNPDLVKNAGKLDRYTDLSRENSPIYKLKDYPWLGVSFNLGAEGTDKDGRSPNKLVSSFDENNSNSNQNLV
YTTEGHPISLGGSQREHTAVAYYLNAKLHLLDKKGIGDIAPGKTVRLGLLKPSIDVRKGNTGLSGILSFNATWDIKDTGQ
IPVKLGLQVKAGRCINKPNPNKNTKAPSPALTAPALWFGPRQDGKVQMYSASVSTYPDSSSSKIFLQNLSRNDDKNKPGR
YSLKPLSENEIKSKEPRFNGRQTVIRLDSGVQLIKLNGSKDEVVIFGNNGNNGTFGIVKEANVNLEADEWKKVLLPWTVR
GPDNDNKFKLINQKPDRYSQRYRIRENGNRDLGDIVNSPIVAVGGYLATSANDGMVHIFKKTGTDERSYNLKLSYIPGTM
ERKDIEGNDSDLAKELRTFAEKGYVGDRYGVDGGFVLRQVNLNGQDRVFMFGAMGLGGRGAYALDLSKINENYPAAAPLF
DVKNGDKNGKNRVEVELGYTVGTPQIGKTRSGKYAAFLASGYAAKDIGSGDNKTALYVYDLNNTLGTPIAKIEVKDGKGG
LSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSNSDPNKWSVRTIFEGTKPITSAPAVSRLKDKRVVIFGTGSDLTEDDV
LDTKEQYIYGIFDDDKAANNVNASRGVLGSGLLEQHLTQENKTLFLNKRSDGSGSKGWAVKLTGGRRVTVKPTVVLRTAF
VTIRKYKDDGCGAETAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKKTAGGKSVPIGCMEKGGKTVCPNGYVYDKP
VNVRYLDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3111 bp        

>NTDB_id=730389 NDL69_RS10270 WP_267720151.1 1933976..1937086(+) (pilC) [Neisseria gonorrhoeae strain 10538]
ATGAATAAAACTTTGAAACGGCAGGTTTTCCGCCATACCGCACTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGGGGCGATGGCGCAAACCCGTCAATACGCTATTGTCATGAACAAACGAAATCAGCCGGAGGTAAAGTGGG
ATGGGCAATATCAAAAATCACAATTAAGGGAAAAAGACGGGGAACGCAAATTTATCTATACGAACCAGAGAAACAAGTTG
GGCCAACAAAACAATTTTATCTCATTCGACAATACCGATGAGCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCAC
AGCCACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGAAAAAGCGCAACAATGCCGTTGATT
GGATTCGTACCACCCGCATCGCGCTGGCAGGCTACAGCTACGAAGGTGTCGTATGCAGAAGCGGCACAGGCTGTCCCAAA
CTTGTCTATAAAACCCGATTTTCCTTCGATAATCCCGACTTGGTAAAAAATGCGGGCAAGCTGGATAGGTACACAGACCT
AAGCCGCGAAAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTA
CCGACAAAGATGGCAGATCACCCAACAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTC
TATACGACAGAAGGCCACCCTATTTCCCTTGGCGGCTCGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAA
ACTGCACCTGCTGGATAAAAAAGGGATTGGAGATATCGCGCCAGGCAAAACAGTGCGGTTGGGTCTCTTGAAGCCGAGCA
TCGATGTGCGGAAAGGAAATACGGGGCTTAGCGGCATTCTATCTTTTAATGCTACGTGGGACATTAAAGATACCGGGCAG
ATTCCGGTCAAGCTCGGCCTGCAAGTCAAAGCAGGCCGCTGCATCAATAAACCGAACCCCAATAAGAATACCAAAGCCCC
TTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGGACCTAGGCAAGATGGTAAGGTGCAGATGTATTCCGCTTCGGTTT
CCACCTACCCCGACAGTTCGAGCAGCAAAATTTTCCTGCAAAACCTTTCCCGCAATGATGACAAAAACAAACCGGGCCGC
TATTCCCTCAAACCCTTGAGTGAGAATGAGATTAAAAGTAAAGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATT
GGATAGCGGCGTACAGCTGATCAAACTGAATGGAAGCAAGGATGAGGTCGTCATTTTTGGAAACAACGGCAACAACGGCA
CTTTCGGCATTGTTAAGGAAGCGAACGTCAATCTTGAAGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGG
GGTCCCGATAATGACAATAAATTTAAATTAATTAACCAAAAACCAGACAGATACAGCCAAAGATACCGCATCCGCGAAAA
CGGCAATCGCGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCGGCGGGTATCTGGCAACTTCTGCCAACGACG
GGATGGTGCATATCTTCAAAAAAACCGGCACGGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGTACGATG
GAGCGTAAGGATATTGAAGGCAATGACTCCGACCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGA
CCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGTCAAGTTAACTTAAACGGACAAGACCGCGTGTTTATGTTCGGCGCAA
TGGGCCTTGGCGGCAGAGGCGCATACGCCTTGGATTTAAGCAAAATCAACGAAAATTATCCAGCCGCCGCTCCCCTGTTT
GATGTCAAAAATGGCGATAAAAACGGCAAAAATCGCGTGGAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGG
CAAAACCCGCAGCGGCAAATACGCCGCCTTCCTCGCTTCCGGTTATGCGGCTAAAGATATTGGCAGCGGCGATAATAAAA
CCGCGCTGTATGTATATGATTTGAACAACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGAAGGACGGCAAAGGCGGG
CTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATAT
GTACCGCTTTGATTTGAGCAATTCCGATCCTAATAAATGGTCTGTAAGGACTATTTTCGAAGGCACAAAACCGATTACCT
CCGCGCCCGCCGTTTCCCGACTGAAAGACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGACCGAAGATGATGTA
CTCGATACGAAAGAACAATATATTTACGGTATCTTTGACGACGATAAGGCGGCGAATAATGTAAATGCAAGCCGCGGCGT
TTTGGGGAGCGGGCTGCTCGAGCAACACCTTACTCAGGAAAATAAAACATTATTCCTGAACAAGAGATCCGACGGTTCGG
GCAGCAAGGGCTGGGCGGTGAAATTGACAGGCGGACGGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTC
GTAACCATCCGCAAATATAAAGACGACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGC
ATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATCACAATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCGCCG
GCGGCAAGTCCGTCCCTATAGGTTGTATGGAAAAAGGCGGTAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCG
GTTAATGTGCGTTATCTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGGTAT
AGACCCCGCCGGCAGGCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGTGTGCGCACCCTGCTGATGAACGATT
TGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(512-847)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.28

100

0.737