Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   NDL71_RS05375 Genome accession   NZ_CP104546
Coordinates   1001816..1004035 (+) Length   739 a.a.
NCBI ID   WP_020996780.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 9035     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 996816..1009035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NDL71_RS05370 (NDL71_01740) - 1001509..1001784 (-) 276 WP_154212468.1 hypothetical protein -
  NDL71_RS05375 (NDL71_01745) comA 1001816..1004035 (+) 2220 WP_020996780.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NDL71_RS05380 (NDL71_01750) comL 1004105..1004908 (-) 804 WP_003687645.1 outer membrane protein assembly factor BamD Machinery gene
  NDL71_RS05385 (NDL71_01755) rluD 1004907..1006031 (+) 1125 WP_003692709.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  NDL71_RS05390 (NDL71_01760) - 1006158..1007132 (-) 975 Protein_1031 bile acid:sodium symporter family protein -
  NDL71_RS05395 (NDL71_01765) - 1007209..1007433 (-) 225 WP_225577482.1 hypothetical protein -
  NDL71_RS05400 (NDL71_01770) pgeF 1007585..1008364 (+) 780 WP_003687651.1 peptidoglycan editing factor PgeF -
  NDL71_RS05405 (NDL71_01775) lptE 1008416..1008895 (+) 480 WP_003687653.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 739 a.a.        Molecular weight: 79931.83 Da        Isoelectric Point: 10.4097

>NTDB_id=730325 NDL71_RS05375 WP_020996780.1 1001816..1004035(+) (comA) [Neisseria gonorrhoeae strain 9035]
MFRRWFLPCWVVGVAVSFALSVVPHWPFWLAAFAVLAVLARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWRAEAVSGVP
LTVEVTDMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGVGGV
GTVGADRVLLHGGSGWGIAVWRSRISRNWRQADADGGLSDGIGLMRALSVGEQSALRPGLWQAFRPLGLTHLVSISGLHV
TMVAVLFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPLAVLGVGTWLSFGLVAALIWACAGRLYEGKRQTAVRGQWAASVLSLVLLGYLFASLPLVSPLVNAVLIPWFSW
VLTPLALLGSVVPFAPLQQAGAFLAEYTLRFLVWLADVSPEFAVAAAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVSYRPEAVPENEAAVTVWDAGQGLSVLVRTANRHLLFDTGTVAAAQTGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLRPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEAELVK
KYGSNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRVYKFYWQKKPFE

Nucleotide


Download         Length: 2220 bp        

>NTDB_id=730325 NDL71_RS05375 WP_020996780.1 1001816..1004035(+) (comA) [Neisseria gonorrhoeae strain 9035]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGCGTGGCAGTTTCGTTCGCACTGTCGGTTGTACCGCATTGGCC
GTTTTGGTTGGCGGCTTTTGCGGTTTTGGCTGTGCTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGAACGGAAGCGGCACTGTCTTCGCAATGGCGGGCGGAGGCGGTTTCAGGCGTGCCT
TTGACGGTGGAAGTGACGGATATGCCGAGGTCGGACGGGCGGCGCGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGCGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGCG
TGCACCCCGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGGGTAGGCGGCGTG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
CAATTGGCGGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGGATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATCTCGGGTTTGCACGTT
ACGATGGTGGCGGTGCTGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCCGCCCGGCCGCGCGC
GTGGGTTTTGGCGGCGGGGTGTGCGGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGTG
TTTTGATGTTGGCGGCGTTCGCGTGGGCGTGGCGCAGGGGAAGACTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCTTTGGCGGTTTTGGGTGTCGGTACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGTGCAGGGCGTTTGTACGAGGGGAAACGGCAAACCGCCGTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCTCTGG
TTTTGCTCGGTTATCTGTTTGCCTCGCTGCCTTTGGTCAGCCCTTTGGTCAATGCGGTGTTGATACCGTGGTTTTCTTGG
GTGTTGACCCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCGCTTCAGCAGGCGGGGGCATTTTTGGCGGAATA
CACTTTGCGGTTTTTGGTGTGGCTTGCCGATGTGTCGCCTGAGTTTGCCGTTGCCGCCGCACCTTTGCCGCTGCTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTATCCTACCGTCCTGAAGCAGTACCTGAAAACGAAGCTGCGGTTACGGTTTGGGATGCGGGGCAGGGCTTGTCGGT
GCTTGTGCGGACGGCAAACCGCCATCTGCTTTTCGATACGGGAACGGTAGCGGCGGCACAAACGGGTATCGTGCCGAGTT
TGAATGCGGCGGGTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGCTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCCGGACAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTCGAGTTTTTGAGGCCGTCTGAACGCAAAAATATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCGGGCGGTGCGGCACTGCTGGTAACGGGAGATTTGGATACGAAAGGTGAGGCGGAGTTGGTTAAA
AAATACGGCTCAAACCTGTACAGCCAGGTTTTGGTTTTGGGACATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCT
CAATGCCGTTTCGCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAGCATCCGACCGAAGCGGTGCAGA
ACCGTGTCCGCGCACACGGCATCAAGTTGTTGCGGACGGATTTGTCGGGCGCGCTGCAATTCGGCTTGGGACGCGGAGGC
GTAAAGGCTCAACGTTTGAGAGTGTATAAATTCTATTGGCAGAAAAAACCGTTTGAGTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(500-677)

Domain of unknown function (DUF4131) (DUF4131)

(7-167)

Competence protein (Competence)

(208-465)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

99.323

100

0.993