Detailed information NTG0729861

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: N2W57_RS13200
• Genome accession: NZ_CP104476
• Coordinates: 2651439..2652326 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain DSM 20231-Res2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2646439..2657326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N2W57_RS13170 (N2W57_13170)	-	2646458..2646550 (+)	93	WP_010956583.1	hypothetical protein	-
N2W57_RS13175 (N2W57_13175)	-	2646658..2647155 (-)	498	WP_001065268.1	glutathione peroxidase	-
N2W57_RS13180 (N2W57_13180)	-	2647165..2647425 (-)	261	WP_001789910.1	hypothetical protein	-
N2W57_RS13185 (N2W57_13185)	-	2647807..2647920 (-)	114	WP_011447078.1	hypothetical protein	-
N2W57_RS13190 (N2W57_13190)	-	2648579..2650579 (-)	2001	WP_000776751.1	ABC transporter permease	-
N2W57_RS13195 (N2W57_13195)	-	2650576..2651331 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
N2W57_RS13200 (N2W57_13200)	braS	2651439..2652326 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
N2W57_RS13205 (N2W57_13205)	braR	2652337..2653002 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
N2W57_RS13210 (N2W57_13210)	-	2653028..2653228 (-)	201	WP_000604728.1	hypothetical protein	-
N2W57_RS13215 (N2W57_13215)	-	2653426..2654850 (+)	1425	WP_000953744.1	alkaline phosphatase	-
N2W57_RS13705	-	2654910..2655011 (-)	102	WP_000731972.1	SE2200 family small protein	-
N2W57_RS13225 (N2W57_13225)	-	2655133..2655588 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
N2W57_RS13230 (N2W57_13230)	-	2655833..2656594 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=729861 N2W57_RS13200 WP_000143419.1 2651439..2652326(-) (braS) [Staphylococcus aureus strain DSM 20231-Res2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=729861 N2W57_RS13200 WP_000143419.1 2651439..2652326(-) (braS) [Staphylococcus aureus strain DSM 20231-Res2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997